3wu1_AB : 3D-footprint complex

structure name	CRYSTAL STRUCTURE OF THE ETS1-RUNX1-DNA TERNARY COMPLEX
reference	Tahirov et al. J.Mol.Biol. 427 1655 2015
source	MUS MUSCULUS / HOMO SAPIENS
experiment	X-ray (resolution=2.40, R-factor=?)
structural superfamily	p53-like transcription factors;"Winged helix" DNA-binding domain;
reference complex	4l18_E 4lg0_B
links to other resources	NAKB PDIdb DNAproDB
protein sequence	> 3wu1_A interface=26,88,116,117,120,123, ladhpgelvrtdspnflcsvlpthwRcnktlpiafkvvalgdvpdgtlvtvmagndenysaelrnataamknqvarfndlrfvgrsgRgksftltitvftnppqvatyhraikitVDgpRepR > 3wu1_B interface=55,56,59,62,63, gpiqlwqfllelltdkscqsfiswtgdgwefklsdpdevarrwgkrknkpkmnyEKlsRglRYyydkniihktagkryvyrfvcdlqsllgytpeelhamldvkp
interface signature	RRVDRR/EKRRY

Estimated binding specificities ?

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# IC=13.851 IC/col=1.065 n_of_columns=13

specificity:

A |   9  76   0   0  96   0   0   0   0   0   4   4   4
C |  79   4   0   0   0   0   0   0   0   0  62   9   9
G |   4   4  96  96   0   0  96   0  96  96   6   4   7
T |   4  12   0   0   0  96   0  96   0   0  24  79  76

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updated Mon Sep 9 21:02:57 2024