3wu1_AB : 3D-footprint complex

structure name	CRYSTAL STRUCTURE OF THE ETS1-RUNX1-DNA TERNARY COMPLEX
reference	Tahirov et al. J.Mol.Biol. 427 1655 2015
source	MUS MUSCULUS / HOMO SAPIENS
experiment	X-ray (resolution=2.40, R-factor=?)
structural superfamily	p53-like transcription factors;"Winged helix" DNA-binding domain;
reference complex	4l18_E 4lg0_B
links to other resources	NAKB PDIdb DNAproDB
protein sequence	> 3wu1_A interface=26,88,116,117,120,123, ladhpgelvrtdspnflcsvlpthwRcnktlpiafkvvalgdvpdgtlvtvmagndenysaelrnataamknqvarfndlrfvgrsgRgksftltitvftnppqvatyhraikitVDgpRepR > 3wu1_B interface=55,56,59,62,63, gpiqlwqfllelltdkscqsfiswtgdgwefklsdpdevarrwgkrknkpkmnyEKlsRglRYyydkniihktagkryvyrfvcdlqsllgytpeelhamldvkp
interface signature	RRVDRR/EKRRY

Estimated binding specificities ?

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# IC=12.690 IC/col=1.057 n_of_columns=12

specificity:

A |  84  72  24   0   0  96   0  84   0   0   0   6
C |   0   6   6  96  96   0  96   0   0  96  96   6
G |   6  12  60   0   0   0   0  12   0   0   0  12
T |   6   6   6   0   0   0   0   0  96   0   0  72

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updated Mon Jan 5 07:58:50 2026