3wu1_AB : 3D-footprint complex

structure name	CRYSTAL STRUCTURE OF THE ETS1-RUNX1-DNA TERNARY COMPLEX
reference	Tahirov et al. J.Mol.Biol. 427 1655 2015
source	MUS MUSCULUS / HOMO SAPIENS
experiment	X-ray (resolution=2.40, R-factor=?)
structural superfamily	"Winged helix" DNA-binding domain;p53-like transcription factors;
reference complex	2stt_A 3wu1_A
links to other resources	NAKB PDIdb DNAproDB
protein sequence	> 3wu1_A interface=26,88,116,117,120,123, ladhpgelvrtdspnflcsvlpthwRcnktlpiafkvvalgdvpdgtlvtvmagndenysaelrnataamknqvarfndlrfvgrsgRgksftltitvftnppqvatyhraikitVDgpRepR > 3wu1_B interface=55,56,59,62,63, gpiqlwqfllelltdkscqsfiswtgdgwefklsdpdevarrwgkrknkpkmnyEKlsRglRYyydkniihktagkryvyrfvcdlqsllgytpeelhamldvkp
interface signature	RRVDRR/EKRRY

Estimated binding specificities ?

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# IC=12.777 IC/col=1.065 n_of_columns=12

specificity:

A |  84  72  18   0   0  96   0  90   0   0   0   6
C |   0   6  12  96  96   0  96   0   0  96  96   6
G |   6  12  60   0   0   0   0   6   0   0   0  12
T |   6   6   6   0   0   0   0   0  96   0   0  72

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updated Wed Jun 24 19:41:05 2026