4a12_ABCD : 3D-footprint complex

structure name	STRUCTURE OF THE GLOBAL TRANSCRIPTION REGULATOR FAPR FROM STAPHYLOCOCCUS AUREUS IN COMPLEX WITH DNA OPERATOR
reference	Buschiazzo et al. 'Plos 9 3108 2013
source	STAPHYLOCOCCUS AUREUS
experiment	X-ray (resolution=3.15, R-factor=?)
structural superfamily	Thioesterase/thiol ester dehydrase-isomerase;"Winged helix" DNA-binding domain;
reference complex	4a12_B
links to other resources	NAKB PDIdb DNAproDB
protein sequence	> 4a12_A interface=35,36,38,39,50, klkkdkrreairqqidsnpfitdhelsdlfqvsiQTiRLdrtylnipelRkriklvaeknydqissieeqefigdliqvnpnvkaqsilditsdsvfhktgiarghvlfaqanslcvalikqptvlthessiqfiekvklndtvraearvvnqtakhyyvevksyvkhtlvfkgnfkmfydkr > 4a12_B interface=36,38,39,41,42,53, etlklkkdkrreairqqidsnpfitdhelsdlfqvSiQTiRLdrtylnipelRkriklvaeknydqissieeqefigdliqvnpnvkaqsilditsdsvfhktgiarghvlfaqanslcvalikqptvlthessiqfiekvklndtvraearvvnqtakhyyvevksyvkhtlvfkgnfkmfydkr > 4a12_C interface=36,38,39,41,42,53, etlklkkdkrreairqqidsnpfitdhelsdlfqvSiQTiRLdrtylnipelRkriklvaeknydqissieeqefigdliqvnpnvkaqsilditsdsvfhktgiarghvlfaqanslcvalikqptvlthessiqfiekvklndtvraearvvnqtakhyyvevksyvkhtlvfkgnfkmfydkr > 4a12_D interface=33,35,36,38,39,50, klkkdkrreairqqidsnpfitdhelsdlfqvSiQTiRLdrtylnipelRkriklvaeknydqissieeqefigdliqvnpnvkaqsilditsdsvfhktgiarghvlfaqanslcvalikqptvlthessiqfiekvklndtvraearvvnqtakhyyvevksyvkhtlvfkgnfkmfydkr
interface signature	QTRLR/SQTRLR/SQTRLR/SQTRLR

Estimated binding specificities ?

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# IC=21.831 IC/col=0.780 n_of_columns=28

specificity:

A |   0  96   0  24  90   1   0  96   1  24  24  24   0   0  96  96  24  69  24   1  96  22   1  24  24  67   0  94
C |   0   0   0  24   1  92   0   0   1  24  24  24  32   0   0   0  24   5  24   3   0  21   4  24  24  11   0   2
G |   0   0   0  24   1   2   1   0  90  24  24  24   0   0   0   0  24   9  24   6   0  53   1  24  24   5   0   0
T |  96   0  96  24   4   1  95   0   4  24  24  24  64  96   0   0  24  13  24  86   0   0  90  24  24  13  96   0

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updated Wed Jul 30 00:25:36 2025