4aae_AB : 3D-footprint complex

structure name	CRYSTAL STRUCTURE OF THE MUTANT D75N I-CREI IN COMPLEX WITH AN ALTERED TARGET (THE FOUR CENTRAL BASES, 2NN REGION, ARE COMPOSED BY AGCG FROM 5' TO 3')
reference	Marenchino et al. 'Nucleic 40 6936 2012
source	CHLAMYDOMONAS REINHARDTII
experiment	X-ray (resolution=2.60, R-factor=?)
structural superfamily	Homing endonucleases;
reference complex	1t9i_B
links to other resources	NAKB PDIdb DNAproDB
protein sequence	> 4aae_A interface=23,25,27,29,31,32,37,43,67,69,138,139, ntkynkefllylagfvdgdgsiIaQiKpNqSYkfkhQlsltfQvtqktqrrwfldklvdeigvgyvRdRgsvsnyilseikplhnfltqlqpflklkqkqanlvlkiieqlpsakespdkflevctwvdqiaalndsKTrkttsetvravld > 4aae_B interface=23,25,27,29,31,32,37,39,43,67,69,72,74,139, ntkynkefllylagfvdgdgsiIaQiKpNqSYkfkhQlSltfQvtqktqrrwfldklvdeigvgyvRdRgsVsNyilseikplhnfltqlqpflklkqkqanlvlkiieqlpsakespdkflevctwvdqiaalndskTrkttsetvravlds
interface signature	IQKNSYQQRRKT/IQKNSYQSQRRVNT

Estimated binding specificities ?

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# IC=21.580 IC/col=0.981 n_of_columns=22

specificity:

A |   0  96  96  85  96   0   0   0  24  24  24  10   5   0  96   0   0   5   0   0   0   0
C |  96   0   0   0   0  96   0   5  24  24  24  66   5   0   0  96   0  10   5  25   0   0
G |   0   0   0  11   0   0  96   0  24  24  24   5  15  96   0   0  96   5   1   1   0  96
T |   0   0   0   0   0   0   0  91  24  24  24  15  71   0   0   0   0  76  90  70  96   0

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updated Mon Jan 5 08:31:40 2026