1t9i_B : 3D-footprint complex

structure name	I-CREI(D20N)/DNA COMPLEX (DNA endonuclease I-CreI)
reference	Monnat Jr. et al. Biochemistry 43 14015 2004
source	Chlamydomonas reinhardtii
experiment	X-ray (resolution=1.60, R-factor=0.194)
structural superfamily	Homing endonucleases;
sequence family	LAGLIDADG endonuclease;
multimeric complexes	1bp7_AB 1bp7_CD 1g9y_AB 1t9i_AB 1t9j_AB 1u0c_AB 1u0d_AB 2i3p_AB 2i3q_AB 4aad_AB 4aae_AB 4aaf_AB 4aag_AB 4aqu_AB 6fb8_AB
redundant complexes	1bp7_D 1g9y_A 1t9j_A 1u0c_A 1u0d_A 2i3p_B 2i3q_A 4aad_A 4aae_A 4aaf_B 4aag_B 4aqu_B 6fb8_A
links to other resources	NAKB PDIdb DNAproDB
protein sequence	> 1t9i_B interface=21,23,25,27,29,31,32,37,39,43,45,65,67,69,71,72,138,139, ntkynkefllylagfvdgngSiIaQiKpNqSYkfkhQlSltfQvTqktqrrwfldklvdeigvgYvRdRgSVsdyilseikplhnfltqlqpflklkqkqanlvlkiieqlpsakespdkflevctwvdqiaalndsKTrkttsetvravldsls
interface signature	SIQKNSYQSQTYRRSVKT

Estimated binding specificities ?

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# IC=10.518 IC/col=1.052 n_of_columns=10

specificity:

A |   0  96  96  64  80   8   0   0   0   8
C |  96   0   0   8   8  80   0   0  96   8
G |   0   0   0   8   0   0  96   0   0  72
T |   0   0   0  16   8   8   0  96   0   8

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Related DNA sequences reported in the literature ?

site	source	matches (E-value)
term: I-CREI
CAAAACGTC	PubMed	1t9i_B(9.99e-16), 1bp7_AB(3.39e-12), 1bp7_CD(3.48e-12), ... (total=25)
GACAGTTTGGT	PubMed	1t9i_B(8.30e-05), 1bp7_AB(8.35e-06), 1bp7_CD(5.19e-06), ... (total=24)

Dendrogram of similar interfaces ?

matrix format

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updated Sat Jan 10 04:57:33 2026