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structure nameI-CREI(D20N)/DNA COMPLEX
(DNA endonuclease I-CreI)
referenceMonnat Jr. et al. Biochemistry 43 14015 2004
sourceChlamydomonas reinhardtii
experimentX-ray (resolution=1.60, R-factor=0.194)
structural superfamilyHoming endonucleases;
sequence familyLAGLIDADG endonuclease;
multimeric complexes1bp7_AB 1bp7_CD 1g9y_AB 1t9i_AB 1t9j_AB 1u0c_AB 1u0d_AB 2i3p_AB 2vbj_AB 2vbo_AB 3mxb_AB 3mxb_RS 4aad_AB 4aae_AB 4aaf_AB 4aag_AB 4aqu_AB 6fb8_AB
redundant complexes1bp7_D 1g9y_A 1t9j_A 1u0c_A 1u0d_A 2i3p_B 2vbj_B 4aad_A 4aae_A 4aaf_B 4aag_B 4aqu_B 6fb8_A 2vbo 3mxb
links to other resourcesNAKB PDBSum PDIdb DNAproDB
protein sequence
interface signatureSIQKNSYQSQTYRRSVKT

Estimated binding specificities ?

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# IC=10.559 IC/col=1.056 n_of_columns=10 specificity:   
A |   8   0  96   0   8  10   8   0   0   0
C |  69   0   0  96   0   0  69   0   0   0
G |   8  96   0   0  80   8  17   0   0  96
T |  11   0   0   0   8  78   2  96  96   0
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Related DNA sequences reported in the literature ?


sitesourcematches (E-value)
term: I-CREI
CAAAACGTCPubMed1t9i_B(9.99e-16), 1bp7_AB(3.39e-12), 1bp7_CD(3.48e-12), ... (total=25)
GACAGTTTGGTPubMed1t9i_B(8.30e-05), 1bp7_AB(8.35e-06), 1bp7_CD(5.19e-06), ... (total=24)

Dendrogram of similar interfaces ?

matrix format

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updated Sun Aug 3 05:56:19 2025