4cn3_AD : 3D-footprint complex

structure name	CRYSTAL STRUCTURE OF THE HUMAN RETINOID X RECEPTOR DNA-BINDING DOMAIN BOUND TO THE HUMAN GDE1SPA RESPONSE ELEMENT
reference	Poussin-Courmontagne et al. Sci.Rep. 5 8216 2015
source	HOMO SAPIENS
experiment	X-ray (resolution=2.35, R-factor=?)
structural superfamily	Glucocorticoid receptor-like DNA-binding domain;
reference complex	6fbq_A
links to other resources	NAKB PDIdb DNAproDB
protein sequence	> 4cn3_A interface=23,26,30,31, tkhicaicgdrssgkhygvyscEgcKgffKRtvrkdltytcrdnkdclidkrqrnrcqycryqkclamgmkreavqee > 4cn3_D interface=22,25,29,30,78, khicaicgdrssgkhygvyscEgcKgffKRtvrkdltytcrddkdclidkrqrnrcqycryqkclamgmkreavqeeR
interface signature	EKKR/EKKRR

Estimated binding specificities ?

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# IC=11.678 IC/col=0.973 n_of_columns=12

specificity:

A |   0   0   0   0  71  24  23   0   0   0   0  75
C |   0   0  14  96  13  24   6   0   0   0  96   9
G |  96   0   0   0   6  24  54  96   0   0   0   6
T |   0  96  82   0   6  24  13   0  96  96   0   6

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updated Mon Jan 5 08:51:57 2026