4cn3_AD : 3D-footprint complex

structure name	CRYSTAL STRUCTURE OF THE HUMAN RETINOID X RECEPTOR DNA-BINDING DOMAIN BOUND TO THE HUMAN GDE1SPA RESPONSE ELEMENT
reference	Poussin-Courmontagne et al. Sci.Rep. 5 8216 2015
source	HOMO SAPIENS
experiment	X-ray (resolution=2.35, R-factor=?)
structural superfamily	Glucocorticoid receptor-like DNA-binding domain;
reference complex	6fbq_A
links to other resources	NAKB PDIdb DNAproDB
protein sequence	> 4cn3_A interface=23,26,30,31, tkhicaicgdrssgkhygvyscEgcKgffKRtvrkdltytcrdnkdclidkrqrnrcqycryqkclamgmkreavqee > 4cn3_D interface=22,25,29,30,78, khicaicgdrssgkhygvyscEgcKgffKRtvrkdltytcrddkdclidkrqrnrcqycryqkclamgmkreavqeeR
interface signature	EKKR/EKKRR

Estimated binding specificities ?

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# IC=11.652 IC/col=0.971 n_of_columns=12

specificity:

A |   0   0   0   0  64  24  16   0   0   0   0  72
C |   0   0   8  96  16  24   0   0   0   8  96   0
G |  96   0   0   0   8  24  64  96   0   0   0   8
T |   0  96  88   0   8  24  16   0  96  88   0  16

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updated Wed Jul 30 00:54:09 2025