4cn3_BC : 3D-footprint complex

structure name	CRYSTAL STRUCTURE OF THE HUMAN RETINOID X RECEPTOR DNA-BINDING DOMAIN BOUND TO THE HUMAN GDE1SPA RESPONSE ELEMENT
reference	Poussin-Courmontagne et al. Sci.Rep. 5 8216 2015
source	HOMO SAPIENS
experiment	X-ray (resolution=2.35, R-factor=?)
structural superfamily	Glucocorticoid receptor-like DNA-binding domain;
reference complex	6fbq_A
links to other resources	NAKB PDIdb DNAproDB
protein sequence	> 4cn3_B interface=21,24,28,29, hicaicgdrssgkhygvyscEgcKgffKRtvrkdltytcrdnkdclidkrqrnrcqycryqkclamgmkreavqee > 4cn3_C interface=28,31,35,36,84, gshmftkhicaicgdrssgkhygvyscEgcKgffKRtvrkdltytcrdnkdclidkrqrnrcqycryqkclamgmkreavqeeR
interface signature	EKKR/EKKRR

Estimated binding specificities ?

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# IC=10.890 IC/col=0.907 n_of_columns=12

specificity:

A |   6   0  85  20   0  10  24  11   0  70  96   0
C |   5   0   1  75  96  16  24   0   0  10   0  96
G |  10  96   5   1   0   5  24   0  96   6   0   0
T |  75   0   5   0   0  65  24  85   0  10   0   0

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updated Mon Jan 5 08:52:06 2026