4cn3_BC : 3D-footprint complex

structure name	CRYSTAL STRUCTURE OF THE HUMAN RETINOID X RECEPTOR DNA-BINDING DOMAIN BOUND TO THE HUMAN GDE1SPA RESPONSE ELEMENT
reference	Poussin-Courmontagne et al. Sci.Rep. 5 8216 2015
source	HOMO SAPIENS
experiment	X-ray (resolution=2.35, R-factor=?)
structural superfamily	Glucocorticoid receptor-like DNA-binding domain;
reference complex	6fbq_A
links to other resources	NAKB PDIdb DNAproDB
protein sequence	> 4cn3_B interface=21,24,28,29, hicaicgdrssgkhygvyscEgcKgffKRtvrkdltytcrdnkdclidkrqrnrcqycryqkclamgmkreavqee > 4cn3_C interface=28,31,35,36,84, gshmftkhicaicgdrssgkhygvyscEgcKgffKRtvrkdltytcrdnkdclidkrqrnrcqycryqkclamgmkreavqeeR
interface signature	EKKR/EKKRR

Estimated binding specificities ?

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# IC=10.905 IC/col=0.909 n_of_columns=12

specificity:

A |   7   0  72  24   0   4  24   0   0  72  96   0
C |   4   0  11  72  96  19  24   0   0   9   0  96
G |   4  96   9   0   0   9  24   5  96  11   0   0
T |  81   0   4   0   0  64  24  91   0   4   0   0

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updated Mon Sep 9 21:46:43 2024