4cn5_AB : 3D-footprint complex

structure name	CRYSTAL STRUCTURE OF THE HUMAN RETINOID X RECEPTOR DNA-BINDING DOMAIN BOUND TO THE HUMAN NR1D1 RESPONSE ELEMENT
reference	Poussin-Courmontagne et al. Sci.Rep. 5 8216 2015
source	HOMO SAPIENS
experiment	X-ray (resolution=2.00, R-factor=?)
structural superfamily	Glucocorticoid receptor-like DNA-binding domain;
reference complex	6fbq_A
links to other resources	NAKB PDIdb DNAproDB
protein sequence	> 4cn5_A interface=25,28,32,33,81, mftkhicaicgdrssgkhygvyscEgcKgffKRtvrkdltytcrdnkdclidkrqrnrcqycryqkclamgmkreavqeeR > 4cn5_B interface=12,22,25,29,30,75, khicaicgdrsSgkhygvyscEgcKgffKRtvrkdltytckdclidkrqrnrcqycryqkclamgmkreavqeeR
interface signature	EKKRR/SEKKRR

Estimated binding specificities ?

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# IC=11.380 IC/col=0.948 n_of_columns=12

specificity:

A |   0   0   6   0  72  24  24   0   0   0   0  66
C |   0   0   6  96   6  24   6   0   0   0  96  12
G |  96  96   6   0   6  24  60  96   0   0   0   6
T |   0   0  78   0  12  24   6   0  96  96   0  12

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updated Mon Jan 5 08:52:17 2026