4g0v_B : 3D-footprint complex

structure name	HUMAN TOPOISOMERASE IIBETA IN COMPLEX WITH DNA AND MITOXANTRONE (DNA topoisomerase 2-beta)
reference	Chan et al. 'Nucleic 41 10630 2013
source	Homo sapiens
experiment	X-ray (resolution=2.55, R-factor=0.163)
structural superfamily	Type II DNA topoisomerase;
sequence family	DNA gyrase/topoisomerase IV, subunit A;
multimeric complexes	4g0u_AB 4g0v_AB 4g0w_AB
reference complex	3qx3_B
links to other resources	NAKB PDIdb DNAproDB
protein sequence	> 4g0v_B interface=55,57,219,222,223,271,272,275,313,365,370, skikgipklddandaggkhslectliltegdsakslavsglgvigrdrygvfplRgKilnvreashkqimenaeinniikivglqykksyddaeslktlrygkimimtdqdqdgshikgllinfihhnwpsllkhgfleefiakeakeyfadmerhrilfryagpeddaaitlafskkkiddrkewltnfmedrrqrrlkhltyndfinkelilfsnsDneRSipslvdgfkpgqrkvlftcfkrndkrevkvaqlagsvaemsayhhgeQAlmMtivnlaqnfvgsnninllqpigqfgtrlhggkdaaspRyiftmlstlarllfpavddnllkflyddnqrvepewyipiipmvlingaegIgtgwAcklpnydareivnnvrrmldgldphpmlpnyknfkgtiqelgqnqyavsgeifvvdrntveitelpvrtwtqvykeqvlepmlngpalisdykeyhtdttvkfvvkmteeklaqaeaaglhkvfklqttltcnsmvlfdhmgclkkyetvqdilkeffdlrlsyyglrkewlvgmlgaestklnnqarfilekiqgkitienrskkdliqmlvqrgyesdpvkawkeaqgpdfnyilnmslwsltkekveelikqrdakgrevndlkrkspsdlwkedlaafveeldkvesqered
interface signature	RKDRSQAMRIA

Estimated binding specificities ?

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# IC=9.151 IC/col=0.654 n_of_columns=14

specificity:

A |   0   0  24  24  24  24  24   0  96  16   0   8   0   0
C |  96   0  24  24  24  24  24  64   0   8  96  56  96   0
G |   0  96  24  24  24  24  24  16   0  64   0  16   0  96
T |   0   0  24  24  24  24  24  16   0   8   0  16   0   0

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updated Mon Dec 18 10:24:13 2023