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structure nameMOUSE ZFP57 ZINC FINGERS IN COMPLEX WITH METHYLATED DNA
(Zinc finger protein 57)
referenceZhang et al. 'Genes 26 2374 2012
sourceMus musculus
experimentX-ray (resolution=0.99, R-factor=0.132)
structural superfamilybeta-beta-alpha zinc fingers;
sequence familyZinc finger, C2H2 type;
reference complex4m9v_C
links to other resourcesNAKB PDBSum PDIdb DNAproDB
protein sequence
interface signatureDASRRSER

Estimated binding specificities ?

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# IC=6.292 IC/col=0.899 n_of_columns=7 specificity:   
A |   7   0   0   7   7   0  73
C |   7   0  96  73   7  96   7
G |   9  96   0   7  75   0   7
T |  73   0   0   9   7   0   9
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Related DNA sequences reported in the literature ?


sitesourcematches (E-value)
term: ZFP57
TGCCGCPubMed4gzn_C(8.73e-10)

Dendrogram of similar interfaces ?

matrix format
  
  ------DCATSC--RGRG----SGEG--RG   L                        +4gzn_C    
                                                     +------1 
  PCYC--RG--DA--RG--RG--DCHG----   L                 !      +2prt_A    
                                                   +-4 
  ------EC--SCKGRG--LT--FCNA----   L               ! !      +1ubd_C    
                                                 +-5 +------2 
  ------QAHTTT--QA--TTLAHGTCDTRG   L             ! !        +1g2d_F    
                                                 ! ! 
  ----RGST--YGYC----QC--TGSTRGYT   L   +---------6 +--------4is1_C    
                                       !         ! 
  ------RGSGDCHGTT--RG--DAEC--RG   L   !         !         +1a1h_A    
                                     --7         +---------3 
  ------LT--ETYC----NTYGQG------   L   !                   +4f6m_A    
                                       ! 
  ------KG--WTKA--------HCHG--RG   L   +-------------------1tf6_A    
                                     

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updated Thu Sep 12 19:24:47 2024