4hf2_AB : 3D-footprint complex

structure name	CRYSTAL STRUCTURE OF E43A ISCR MUTANT BOUND TO ITS PROMOTER
reference	Rajagopalan et al. Nat.Struct.Mol.Biol. 20 740 2013
source	Escherichia coli
experiment	X-ray (resolution=2.99, R-factor=?)
structural superfamily	"Winged helix" DNA-binding domain;
reference complex	4hf1_A
links to other resources	NAKB PDIdb DNAproDB
protein sequence	> 4hf2_A interface=38,40,41,44,59,61, mrltskgryavtamldvalnseagpvpladiserqgiSlSYlaQlfsrlrknglvssvRgPgggyllgkdassiavgevisavdesalthalwrdlsdrltgflnnitlgelvnn > 4hf2_B interface=40,41,44,59,61, mrltskgryavtamldvalnseagpvpladiserqgislSYlaQlfsrlrknglvssvRgPgggyllgkdassiavgevisavdggdkalthalwrdlsdrltgflnnitlgelvnnqevl
interface signature	SSYQRP/SYQRP

Estimated binding specificities ?

readout + contact

# IC=11.748 IC/col=0.511 n_of_columns=23

specificity:

A |  95  24  13  24  24  24   0  96   6  24  24  24  24  24   1   0  96   3  24  24   1  13   0
C |   0  24  11  24  24  24  96   0  82  24  24  24  24  24  13   0   0   3  24  24   3  23   0
G |   0  24  23  24  24  24   0   0   1  24  24  24  24  24  78   0   0   4  24  24   5  11   0
T |   1  24  49  24  24  24   0   0   7  24  24  24  24  24   4  96   0  86  24  24  87  49  96

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updated Mon Jan 5 09:24:29 2026