4hf2_AB : 3D-footprint complex

structure name	CRYSTAL STRUCTURE OF E43A ISCR MUTANT BOUND TO ITS PROMOTER
reference	Rajagopalan et al. Nat.Struct.Mol.Biol. 20 740 2013
source	Escherichia coli
experiment	X-ray (resolution=2.99, R-factor=?)
structural superfamily	"Winged helix" DNA-binding domain;
reference complex	4hf1_A
links to other resources	NAKB PDIdb DNAproDB
protein sequence	> 4hf2_A interface=38,40,41,44,59,61, mrltskgryavtamldvalnseagpvpladiserqgiSlSYlaQlfsrlrknglvssvRgPgggyllgkdassiavgevisavdesalthalwrdlsdrltgflnnitlgelvnn > 4hf2_B interface=40,41,44,59,61, mrltskgryavtamldvalnseagpvpladiserqgislSYlaQlfsrlrknglvssvRgPgggyllgkdassiavgevisavdggdkalthalwrdlsdrltgflnnitlgelvnnqevl
interface signature	SSYQRP/SYQRP

Estimated binding specificities ?

readout + contact

# IC=11.214 IC/col=0.488 n_of_columns=23

specificity:

A |  89  69  71  24  24  83   0  96   8  24  24  24  24  24   3   0   0  24  24  24  55  24   2
C |   3  16   9  24  24   2   0   0  83  24  24  24  24  24   8   0   0  24  24  24  18  24   2
G |   2   5   8  24  24   9   0   0   3  24  24  24  24  24  83   0  96  24  24  24   6  24   3
T |   2   6   8  24  24   2  96   0   2  24  24  24  24  24   2  96   0  24  24  24  17  24  89

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updated Wed Jun 24 21:04:15 2026