4hf2_AB : 3D-footprint complex

structure name	CRYSTAL STRUCTURE OF E43A ISCR MUTANT BOUND TO ITS PROMOTER
reference	Rajagopalan et al. Nat.Struct.Mol.Biol. 20 740 2013
source	Escherichia coli
experiment	X-ray (resolution=2.99, R-factor=?)
structural superfamily	"Winged helix" DNA-binding domain;
reference complex	4hf1_A
links to other resources	NAKB PDIdb DNAproDB
protein sequence	> 4hf2_A interface=38,40,41,44,59,61, mrltskgryavtamldvalnseagpvpladiserqgiSlSYlaQlfsrlrknglvssvRgPgggyllgkdassiavgevisavdesalthalwrdlsdrltgflnnitlgelvnn > 4hf2_B interface=40,41,44,59,61, mrltskgryavtamldvalnseagpvpladiserqgislSYlaQlfsrlrknglvssvRgPgggyllgkdassiavgevisavdggdkalthalwrdlsdrltgflnnitlgelvnnqevl
interface signature	SSYQRP/SYQRP

Estimated binding specificities ?

readout + contact

# IC=11.915 IC/col=0.518 n_of_columns=23

specificity:

A |  93  51  96  24  24  78   0  96   4  24  24  24  24  24   6   0   0  24  24  24  60  24   3
C |   3  17   0  24  24   5   0   0  82  24  24  24  24  24   1   0   0  24  24  24  20  24   5
G |   0  18   0  24  24   3   0   0   0  24  24  24  24  24  89   0  96  24  24  24  10  24   3
T |   0  10   0  24  24  10  96   0  10  24  24  24  24  24   0  96   0  24  24  24   6  24  85

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updated Wed Jul 30 01:23:46 2025