4hf1_A : 3D-footprint complex

structure name	CRYSTAL STRUCTURE OF ISCR BOUND TO ITS PROMOTER (HTH-type transcriptional regulator IscR)
reference	Rajagopalan et al. Nat.Struct.Mol.Biol. 20 740 2013
source	Escherichia coli
experiment	X-ray (resolution=2.22, R-factor=0.205)
structural superfamily	"Winged helix" DNA-binding domain;
sequence family	Transcriptional regulator;
multimeric complexes	4chu_AB 4hf1_AB 4hf2_AB
redundant complexes	4chu_A 4hf2_A
links to other resources	NAKB PDIdb DNAproDB
protein sequence	> 4hf1_A interface=38,40,41,43,44,59,61, mrltskgryavtamldvalnseagpvpladiserqgiSlSYlEQlfsrlrknglvssvRgPgggyllgkdassiavgevisavdesvdalthalwrdlsdrltgflnnitlgelvnnqevldvsgrqht
interface signature	SSYEQRP

Estimated binding specificities ?

readout + contact

# IC=2.150 IC/col=0.430 n_of_columns=5

specificity:

A |   7  26  28   8  86
C |  73  50  22  14   4
G |   9  11  24   7   3
T |   7   9  22  67   3

scan!

Dendrogram of similar interfaces ?

matrix format

  
  TT------KATTQTTGLTRTKAFTYT   L       +-----------------------------2p7c_B    
                                     +-1 
  ----------------YG--------       +-2 +-----------------------------3eyi_B    
                                   ! ! 
  --VTSARGTA--RT------------   L --3 +-----------------------------6za3_B    
                                   ! 
  ----EGRTRGRGYT------------   L   +-----------------------------4yo2_A

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updated Sun Aug 3 08:06:34 2025