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3D-footprint cannot reliably estimate the specificity of 'Nucleic acid-binding proteins', as they bind to single-stranded DNA and thus accumulate more base contacts.


Dendrogram of similar interfaces ?

matrix format
structure nameCRYSTAL STRUCTURE OF SCHIZOSACCHAROMYCES POMBE POT1PC BOUND TO SSDNA (ACGGTTACGGT)
(Protection of telomeres protein 1)
referenceDickey et al. Structure 21 121 2013
sourceSchizosaccharomyces pombe
experimentX-ray (resolution=2.10, R-factor=0.198)
structural superfamilyNucleic acid-binding proteins;
links to other resourcesNAKB PDBSum PDIdb DNAproDB
protein sequence
  
  ------KG--WGYT----------YCFA--MASGSGRG------RT--IG--WGDG------KG--DTHTLTYAEGIGHG----------   L                          +----4hja_A    
                                                                                                             +------------1 
  --YT------------------------------------------------YGDG--ST--------------------HTYTRT----   L           +-2            +----3kjp_A    
                                                                                                           ! ! 
  ----FG--YG----------YT------------------------------------------RG--YG--------------------   L     +-----4 +-----------------2i0q_A    
                                                                                                     !     ! 
  --------------------------------------------NT--SG--WG--------KG----FG----EG----------EGTG         !     ! +-----------------3u58_C    
                                                                                                   +-5     +-3 
  ------------------------------------------QC--HC--FA--------TG--RG--YC--RC----------------       ! !       +-----------------6bwy_A    
                                                                                                 --6 ! 
  TGYG----SG--DGKGATFT--SGVGNGYTLG----YG------KG------YT------------------------------------   L   ! +------------------------1s40_A    
                                                                                                   ! 
  --YT----------------------NTYT----SGFGRGET--HA--LT------IT--------------------------LT----   L   +-------------------------6lbr_A    
                                                                                                 

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updated Fri Sep 13 18:19:55 2024