7cuh_A : 3D-footprint complex

3D-footprint cannot reliably estimate the specificity of 'Nucleic acid-binding proteins', as they bind to single-stranded DNA and thus accumulate more base contacts.

Dendrogram of similar interfaces ?

matrix format

structure name	CRYSTAL STRUCTURE OF FISSION YEAST POT1 AND SSDNA (Protection of telomeres protein 1)
reference	Sun et al. 'Plos 18 e1010308 2022
source	Schizosaccharomyces pombe (strain 972 / ATCC 24843) / Schizosaccharomyces pombe (strain 972 / ATCC 24843)
experiment	X-ray (resolution=3.00, R-factor=0.269)
structural superfamily	Nucleic acid-binding proteins;
sequence family	Telomerebinding protein alpha subunit, cen;
links to other resources	NAKB PDIdb DNAproDB
protein sequence	> 7cuh_A interface=51,55,57,77,79,81,83,104,106,108,113,115,117,118,189,191,192,195,196,200,211,213,221,232,234,236,237,261,263,265,267,269,271,273,275,276,277,279,280, slqlnellnageykigeltfqsirssqelqkkntivnlfgivkdftpsrqSlhgTkDwvttvylwdptcdtssiglQiHlFsKqgndlpvikqvgqplllhqiTlRsYrdrtQgLsKDqfryalwpdfssnskdtlcpqpmprlmktgdkeeqfalllnkiwdeqtvsfsllsqitphqrcsfyaqviKtWYsdKNftlYvtdytenelfFpMspytsssRwrgpfgrfsiRcIlWDehdfycrnyikegdyvvmknvrtKiDhLgYlEcIlHgDSAkRYnmsiekvdseepelneiksrkrlyv

  
  --STTTDTQCHCFTKTTGRCYC--QCLG--KGDG--KGWTYTKGNGYGFAMA----RGRTIGWGDG----KG--DA--LTYAEGIGHGDGSGAGRGYG--   L                 +--------------7cuh_A    
                                                                                                                   +-------1 
  ------------------------------------KGWGYT----YCFAMASGSGRGRTIGWGDG----KG--DTHTLTYAEGIGHG------------   L     +---2       +--------------4hja_A    
                                                                                                               !   ! 
  NGSTTTDTQCHCFA--TGRGYCRCQCLGSGKGDG------------------------------------------------------------------       +-3   +----------------------6bwy_A    
                                                                                                             ! ! 
  ----------------------------------YT--------------------------YGDGST----HT----------------------YTRT   L --4 +--------------------------7qxs_P    
                                                                                                             ! 
  ----------------------------------QT----------------------RTWT----LTTT--KT--FTQT----ST------------HT       +---------------------------4gnx_B

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updated Sat Sep 14 02:07:13 2024