4hn6_AB : 3D-footprint complex

structure name	GR DNA BINDING DOMAIN R460D/D462R - TSLP NGRE COMPLEX
reference	Ortlund et al. Nat.Struct.Mol.Biol. 20 53 2013
source	Homo sapiens
experiment	X-ray (resolution=2.55, R-factor=?)
structural superfamily	Glucocorticoid receptor-like DNA-binding domain;
reference complex	3g9m_B
links to other resources	NAKB PDIdb DNAproDB
protein sequence	> 4hn6_A interface=24,25,29, klclvcsdeasgchygvltcgscKVffkRavegqhnylcagdnrciidkirrkncpacryrkclqagmnlea > 4hn6_B interface=24,25,29, klclvcsdeasgchygvltcgscKVffkRavegqhnylcagdnrciidkirrkncpacryrkclqagmnlea
interface signature	KVR/KVR

Estimated binding specificities ?

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# IC=8.370 IC/col=0.598 n_of_columns=14

specificity:

A |   0   0   0  24  24  24  24  19   0  24  82  18  77   0
C |  96   0  96  24  24  24  24   7   4  24  11  14   0   3
G |   0  96   0  24  24  24  24  59  92  24   3  51  18  88
T |   0   0   0  24  24  24  24  11   0  24   0  13   1   5

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updated Mon Jan 5 09:25:32 2026