4hn6_AB : 3D-footprint complex

structure name	GR DNA BINDING DOMAIN R460D/D462R - TSLP NGRE COMPLEX
reference	Ortlund et al. Nat.Struct.Mol.Biol. 20 53 2013
source	Homo sapiens
experiment	X-ray (resolution=2.55, R-factor=?)
structural superfamily	Glucocorticoid receptor-like DNA-binding domain;
reference complex	3g9m_B
links to other resources	NAKB PDIdb DNAproDB
protein sequence	> 4hn6_A interface=24,25,29, klclvcsdeasgchygvltcgscKVffkRavegqhnylcagdnrciidkirrkncpacryrkclqagmnlea > 4hn6_B interface=24,25,29, klclvcsdeasgchygvltcgscKVffkRavegqhnylcagdnrciidkirrkncpacryrkclqagmnlea
interface signature	KVR/KVR

Estimated binding specificities ?

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# IC=7.983 IC/col=0.570 n_of_columns=14

specificity:

A |   0   0   2  24  24  24  24  11   1  24  89  13  75   2
C |  96   0  89  24  24  24  24  13   2  24   2  13   2   2
G |   0  96   3  24  24  24  24  56  91  24   2  54  16  89
T |   0   0   2  24  24  24  24  16   2  24   3  16   3   3

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updated Wed Jun 24 21:05:18 2026