4hn6_AB : 3D-footprint complex

structure name	GR DNA BINDING DOMAIN R460D/D462R - TSLP NGRE COMPLEX
reference	Ortlund et al. Nat.Struct.Mol.Biol. 20 53 2013
source	Homo sapiens
experiment	X-ray (resolution=2.55, R-factor=?)
structural superfamily	Glucocorticoid receptor-like DNA-binding domain;
reference complex	5e69_A
links to other resources	NAKB PDIdb DNAproDB
protein sequence	> 4hn6_A interface=24,25,29, klclvcsdeasgchygvltcgscKVffkRavegqhnylcagdnrciidkirrkncpacryrkclqagmnlea > 4hn6_B interface=24,25,29, klclvcsdeasgchygvltcgscKVffkRavegqhnylcagdnrciidkirrkncpacryrkclqagmnlea
interface signature	KVR/KVR

Estimated binding specificities ?

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# IC=8.398 IC/col=0.600 n_of_columns=14

specificity:

A |   0   0   0  24  24  24  24  18   3  24  90  15  92   0
C |  96   0  96  24  24  24  24  21   0  24   0  20   0  21
G |   0  96   0  24  24  24  24  34  93  24   0  46   1  74
T |   0   0   0  24  24  24  24  23   0  24   6  15   3   1

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updated Wed Jul 30 01:24:40 2025