4ihw_AB : 3D-footprint complex

structure name	CRYSTAL STRUCTURE OF FIS BOUND TO 27 BP INOSINE SUBSTITUTED DNA F28- DI (AAATTTGTTTGAICITTGAGCAAATTT)
reference	Hancock et al. 'Nucleic 41 6750 2013
source	Escherichia coli
experiment	X-ray (resolution=2.70, R-factor=?)
structural superfamily	Homeodomain-like;
reference complex	5ds9_A
links to other resources	NAKB PDIdb DNAproDB
protein sequence	> 4ihw_A interface=68,77,78,80,82,83, sdvltvstvnsqdqvtqkplrdsvkqalknyfaqlngqdvndlyelvlaeveqplldmvmqytrgnqTraalmmgiNRgTlRKklkkygmn > 4ihw_B interface=75,84,85,89, mfeqrvnsdvltvstvnsqdqvtqkplrdsvkqalknyfaqlngqdvndlyelvlaeveqplldmvmqytrgnqTraalmmgiNRgtlRkklkkygmn
interface signature	TNRTRK/TNRR

Estimated binding specificities ?

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# IC=6.737 IC/col=0.396 n_of_columns=17

specificity:

A |   0   0   3  24  24   9  24  24  24  24  24   5  55  24  24   0  88
C |   5   0  17  24  24  22  24  24  24  24  24   0   5  24  24  96   0
G |   3  96  14  24  24  51  24  24  24  24  24   3  33  24  24   0   5
T |  88   0  62  24  24  14  24  24  24  24  24  88   3  24  24   0   3

scan!

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updated Wed Jun 24 21:09:45 2026