4iqr_AB : 3D-footprint complex

structure name	MULTI-DOMAIN ORGANIZATION OF THE HNF4ALPHA NUCLEAR RECEPTOR COMPLEX ON DNA
reference	Rastinejad et al. Nature 495 394 2013
source	Homo sapiens
experiment	X-ray (resolution=2.90, R-factor=?)
structural superfamily	Nuclear receptor ligand-binding domain;Glucocorticoid receptor-like DNA-binding domain;
reference complex	4iqr_B
links to other resources	NAKB PDIdb DNAproDB
protein sequence	> 4iqr_A interface=21,24,28,29, alcaicgdratgkhygasscDgcKgffRRsvrknhmyscrfsrqcvvdkdkrnqcrycrlkkcfragmkkeavqneinallqaevlsrqitspvsgingdirakkiasiadvcesmkeqllvlvewakyipafcelplddqvallrahagehlllgatkrsmvfkdvlllgndyivprhcpelaemsrvsirildelvlpfqelqiddneyaylkaiiffdpdakglsdpgkikrlrsqvqvsledyindrqydsrgrfgelllllptlqsitwqmieqiqfiklfgmakidnllqemllgg > 4iqr_B interface=21,24,28,29,77, alcaicgdratgkhygasscDgcKgffRRsvrknhmyscrfsrqcvvdkdkrnqcrycrlkkcfragmkkeavqneRdristrrssyedsslpsinallqaevlsdirakkiasiadvcesmkeqllvlvewakyipafcelplddqvallrahagehlllgatkrsmvfkdvlllgndyivprhcpelaemsrvsirildelvlpfqelqiddneyaylkaiiffdpdakglsdpgkikrlrsqvqvsledyindrqydsrgrfgelllllptlqsitwqmieqiqfiklfgmakidnllqemllgg
interface signature	DKRR/DKRRR

Estimated binding specificities ?

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# IC=9.531 IC/col=0.866 n_of_columns=11

specificity:

A |   0  59   1   0   4  24   1   0  54   0   0
C |   0   4  91  96  13  24   0   0  18  96  96
G |  96  18   4   0  20  24   4   9  15   0   0
T |   0  15   0   0  59  24  91  87   9   0   0

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updated Mon Sep 9 22:19:48 2024