4iqr_AB : 3D-footprint complex

structure name	MULTI-DOMAIN ORGANIZATION OF THE HNF4ALPHA NUCLEAR RECEPTOR COMPLEX ON DNA
reference	Rastinejad et al. Nature 495 394 2013
source	Homo sapiens
experiment	X-ray (resolution=2.90, R-factor=?)
structural superfamily	Nuclear receptor ligand-binding domain;Glucocorticoid receptor-like DNA-binding domain;
reference complex	4iqr_B
links to other resources	NAKB PDIdb DNAproDB
protein sequence	> 4iqr_A interface=21,24,28,29, alcaicgdratgkhygasscDgcKgffRRsvrknhmyscrfsrqcvvdkdkrnqcrycrlkkcfragmkkeavqneinallqaevlsrqitspvsgingdirakkiasiadvcesmkeqllvlvewakyipafcelplddqvallrahagehlllgatkrsmvfkdvlllgndyivprhcpelaemsrvsirildelvlpfqelqiddneyaylkaiiffdpdakglsdpgkikrlrsqvqvsledyindrqydsrgrfgelllllptlqsitwqmieqiqfiklfgmakidnllqemllgg > 4iqr_B interface=21,24,28,29,77, alcaicgdratgkhygasscDgcKgffRRsvrknhmyscrfsrqcvvdkdkrnqcrycrlkkcfragmkkeavqneRdristrrssyedsslpsinallqaevlsdirakkiasiadvcesmkeqllvlvewakyipafcelplddqvallrahagehlllgatkrsmvfkdvlllgndyivprhcpelaemsrvsirildelvlpfqelqiddneyaylkaiiffdpdakglsdpgkikrlrsqvqvsledyindrqydsrgrfgelllllptlqsitwqmieqiqfiklfgmakidnllqemllgg
interface signature	DKRR/DKRRR

Estimated binding specificities ?

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# IC=9.783 IC/col=0.889 n_of_columns=11

specificity:

A |   0  80   3   0  11  24   3   3  79   0   0
C |   0   3  90  96   7  24   3   3   7  96  96
G |  96   3   3   0  17  24   6  14   3   0   0
T |   0  10   0   0  61  24  84  76   7   0   0

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updated Wed Jul 30 01:29:20 2025