4iqr_AB : 3D-footprint complex

structure name	MULTI-DOMAIN ORGANIZATION OF THE HNF4ALPHA NUCLEAR RECEPTOR COMPLEX ON DNA
reference	Rastinejad et al. Nature 495 394 2013
source	Homo sapiens
experiment	X-ray (resolution=2.90, R-factor=?)
structural superfamily	Nuclear receptor ligand-binding domain;Glucocorticoid receptor-like DNA-binding domain;
reference complex	4iqr_B
links to other resources	NAKB PDIdb DNAproDB
protein sequence	> 4iqr_A interface=21,24,28,29, alcaicgdratgkhygasscDgcKgffRRsvrknhmyscrfsrqcvvdkdkrnqcrycrlkkcfragmkkeavqneinallqaevlsrqitspvsgingdirakkiasiadvcesmkeqllvlvewakyipafcelplddqvallrahagehlllgatkrsmvfkdvlllgndyivprhcpelaemsrvsirildelvlpfqelqiddneyaylkaiiffdpdakglsdpgkikrlrsqvqvsledyindrqydsrgrfgelllllptlqsitwqmieqiqfiklfgmakidnllqemllgg > 4iqr_B interface=21,24,28,29,77, alcaicgdratgkhygasscDgcKgffRRsvrknhmyscrfsrqcvvdkdkrnqcrycrlkkcfragmkkeavqneRdristrrssyedsslpsinallqaevlsdirakkiasiadvcesmkeqllvlvewakyipafcelplddqvallrahagehlllgatkrsmvfkdvlllgndyivprhcpelaemsrvsirildelvlpfqelqiddneyaylkaiiffdpdakglsdpgkikrlrsqvqvsledyindrqydsrgrfgelllllptlqsitwqmieqiqfiklfgmakidnllqemllgg
interface signature	DKRR/DKRRR

Estimated binding specificities ?

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# IC=9.363 IC/col=0.851 n_of_columns=11

specificity:

A |   0   0   9  77  86  24  56   0   0  10   0
C |   0   0   9  13   4  24  13   0   0   9  96
G |  96  96  13   2   6  24   9  96  96  13   0
T |   0   0  65   4   0  24  18   0   0  64   0

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updated Mon Jan 5 09:30:51 2026