| structure name | MULTI-DOMAIN ORGANIZATION OF THE HNF4ALPHA NUCLEAR RECEPTOR COMPLEX ON DNA (Hepatocyte nuclear factor 4-alpha) |
| reference | Rastinejad et al. Nature 495 394 2013 |
| source | Homo sapiens |
| experiment | X-ray (resolution=2.90, R-factor=0.241) |
| structural superfamily | Nuclear receptor ligand-binding domain;Glucocorticoid receptor-like DNA-binding domain; |
| sequence family | Ligandbinding domain of nuclear hormon; Zinc finger, C4 type two domains; |
| multimeric complexes | 4iqr_AB 4iqr_EF |
| links to other resources | NAKB  PDIdb DNAproDB |
| protein sequence | |
| interface signature | DKRRR |
Estimated binding specificities ?
readout + contact |  |
A | 73 0 0 9 7 73 C | 7 0 0 7 73 7 G | 7 96 96 7 7 9 T | 9 0 0 73 9 7scan! |
Dendrogram of similar interfaces ?
matrix format--DAKG--RGRG--RT-------- L +--------------------4iqr_B ! --EAKG--RTRTRT---------- ! +2han_B ! +-------------1 --EAKG--RTRTRT---------- ! ! +4umm_E +-8 ! CAECKG--KGRG------------ L ! ! ! +---6l6q_B ! ! +---6 ! ----KAVA--RA------------ L ! ! ! ! +----4 +5e69_A ! ! ! ! ! ! +-2 --ECKG--KGRG------------ L ! ! ! ! ! +---3 +2ff0_A +-9 +--7 +----5 ! --ETKGAT--RG------------ L ! ! ! ! +1lat_A ! ! ! ! ----KGVT--RG------------ L ! ! ! +--------2c7a_B +---10 ! ! ----KGVT--RG------------ ! ! ! +-----------------5emp_A ! ! ! --ECKGAG--RG------------ L -11 ! +----------------------4ond_A ! ! --ECKGAGKGRG------------ L ! +-----------------------1hcq_E ! ----------------RAIAQTNA L +----------------------------6es3_K |
home
updated Tue Dec 19 09:00:42 2023