4iqr_EF : 3D-footprint complex

structure name	MULTI-DOMAIN ORGANIZATION OF THE HNF4ALPHA NUCLEAR RECEPTOR COMPLEX ON DNA
reference	Rastinejad et al. Nature 495 394 2013
source	Homo sapiens
experiment	X-ray (resolution=2.90, R-factor=?)
structural superfamily	Nuclear receptor ligand-binding domain;Glucocorticoid receptor-like DNA-binding domain;
reference complex	4iqr_B
links to other resources	NAKB PDIdb DNAproDB
protein sequence	> 4iqr_E interface=21,24,28,29, alcaicgdratgkhygasscDgcKgffRRsvrknhmyscrfsrqcvvdkdkrnqcrycrlkkcfragmkkeavqnpsinallqaevlsrqitspvsgingdirakkiasiadvcesmkeqllvlvewakyipafcelplddqvallrahagehlllgatkrsmvfkdvlllgndyivprhcpelaemsrvsirildelvlpfqelqiddneyaylkaiiffdpdakglsdpgkikrlrsqvqvsledyindrqydsrgrfgelllllptlqsitwqmieqiqfiklfgmakidnllqemllgg > 4iqr_F interface=21,24,28,29,77, alcaicgdratgkhygasscDgcKgffRRsvrknhmyscrfsrqcvvdkdkrnqcrycrlkkcfragmkkeavqneRdristrrssyedsslpsinallqaevlsrsgingdirakkiasiadvcesmkeqllvlvewakyipafcelplddqvallrahagehlllgatkrsmvfkdvlllgndyivprhcpelaemsrvsirildelvlpfqelqiddneyaylkaiiffdpdakglsdpgkikrlrsqvqvsledyindrqydsrgrfgelllllptlqsitwqmieqiqfiklfgmakidnllqemllgg
interface signature	DKRR/DKRRR

Estimated binding specificities ?

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# IC=11.410 IC/col=0.951 n_of_columns=12

specificity:

A |   0   0  78   0   0   6  24   0   6  78   0   6
C |   0   0   6  96  96   6  24   0   6   6  96  78
G |   0  96   6   0   0   6  24   0  78   6   0   6
T |  96   0   6   0   0  78  24  96   6   6   0   6

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updated Wed Jun 24 21:10:56 2026