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structure nameHUMAN TOPOISOMERASE IIBETA IN COMPLEX WITH DNA
(DNA topoisomerase 2-beta)
referenceChan et al. 'Nucleic 41 10630 2013
sourceHomo sapiens
experimentX-ray (resolution=2.30, R-factor=0.178)
structural superfamilyType II DNA topoisomerase;
sequence familyDNA gyrase/topoisomerase IV, subunit A;
multimeric complexes4g0u_AB 4g0v_AB 4g0w_AB
reference complex3qx3_B
links to other resourcesNAKB PDBSum PDIdb DNAproDB
protein sequence
interface signatureRKDRSQAMIA

Estimated binding specificities ?

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# IC=2.916 IC/col=0.583 n_of_columns=5 specificity:   
A |   0   4  15  11   9
C |  95   3  19  12  63
G |   0  85  28  62  12
T |   1   4  34  11  12
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updated Mon Dec 18 10:35:10 2023