4kfc_AB : 3D-footprint complex

structure name	CRYSTAL STRUCTURE OF A HYPERACTIVE MUTANT OF RESPONSE REGULATOR KDPE COMPLEXED TO ITS PROMOTER DNA
reference	Narayanan et al. 'Nat 5 3282 2014
source	Escherichia coli
experiment	X-ray (resolution=2.53, R-factor=?)
structural superfamily	CheY-like;
reference complex	4kfc_B
links to other resources	NAKB PDIdb DNAproDB
protein sequence	> 4kfc_A interface=188,189,191,192,193, amanvlivedeqairrflrtalegdgmrvfeaetlqrglleaatrkpdliildlglpdgdgiefirdlrqwsavpvivlsarseesdkiaaldagaddylskpfgigelqarlrvalrrhsapdplvkfsdvtvdlaarvihrgeeevhltpiefrllavllnnagkvltqrqllnqvwgpnavehsHYlRIYmghlrqkleqdparprhfitatgigyrfml > 4kfc_B interface=189,192,193,194, amanvlivedeqairrflrtalegdgmrvfeaetlqrglleaatrkpdliildlglpdgdgiefirdlrqwsavpvivlsarseesdkiaaldagaddylskpfgigelqarlrvalrrhstapdplvkfsdvtvdlaarvihrgeeevhltpiefrllavllnnagkvltqrqllnqvwgpnavehsHylRIYmghlrqkleqdparprhfitatgigyrfml
interface signature	HYRIY/HRIY

Estimated binding specificities ?

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# IC=11.274 IC/col=0.626 n_of_columns=18

specificity:

A |   0   2   4  96  88  58  65  24  24  24  24   0  24  24  65  96  78  90
C |   0   2   2   0   4  12  10  24  24  24  24   0  24  24  12   0  14   4
G |   0  90   2   0   2  16  10  24  24  24  24   0  24  24   9   0   2   0
T |  96   2  88   0   2  10  11  24  24  24  24  96  24  24  10   0   2   2

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updated Mon Jan 5 10:01:33 2026