4kfc_B : 3D-footprint complex

structure name	CRYSTAL STRUCTURE OF A HYPERACTIVE MUTANT OF RESPONSE REGULATOR KDPE COMPLEXED TO ITS PROMOTER DNA (KDP operon transcriptional regulatory protein KdpE)
reference	Narayanan et al. 'Nat 5 3282 2014
source	Escherichia coli
experiment	X-ray (resolution=2.53, R-factor=0.208)
structural superfamily	CheY-like;
sequence family	Response regulator receiver domain; Transcriptional regulatory protein, C te;
multimeric complexes	4kfc_AB 4kny_AB
redundant complexes	4kny_B
links to other resources	NAKB PDIdb DNAproDB
protein sequence	> 4kfc_B interface=189,192,193,194, amanvlivedeqairrflrtalegdgmrvfeaetlqrglleaatrkpdliildlglpdgdgiefirdlrqwsavpvivlsarseesdkiaaldagaddylskpfgigelqarlrvalrrhstapdplvkfsdvtvdlaarvihrgeeevhltpiefrllavllnnagkvltqrqllnqvwgpnavehsHylRIYmghlrqkleqdparprhfitatgigyrfml
interface signature	HRIY

Estimated binding specificities ?

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# IC=4.007 IC/col=0.801 n_of_columns=5

specificity:

A |   0  11   9  96  67
C |   0   9   9   0  11
G |   0  67   9   0   9
T |  96   9  69   0   9

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Dendrogram of similar interfaces ?

matrix format

  
  --------------------RG--DTVT--STRGWT   L               +---------------------6lxn_A    
                                                 +-------2 
  ------------------------------YGRG--           !       !                   +-4wcg_A    
                                               +-3       +-------------------1 
  --------------RC--------------------         ! !                           +-6l9z_S    
                                             +-4 ! 
  ------------TA----------------------       ! ! +-----------------------------4p0p_A    
                                           --5 ! 
  ----------------LGTAKGTA--HTRG------   L   ! +-----------------------------6jhe_A    
                                             ! 
  FTDTITVTATLG------------------------   L   +-----------------------------3zh2_C

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updated Sun Aug 3 08:12:05 2025