4l0z_AB : 3D-footprint complex

structure name	CRYSTAL STRUCTURE OF RUNX1 AND ETS1 BOUND TO TCR ALPHA PROMOTER (CRYSTAL FORM 2)
reference	Leukemia 28 2040 2014
source	MUS MUSCULUS / HOMO SAPIENS
experiment	X-ray (resolution=2.70, R-factor=?)
structural superfamily	p53-like transcription factors;"Winged helix" DNA-binding domain;
reference complex	4l18_E 4lg0_B
links to other resources	NAKB PDIdb DNAproDB
protein sequence	> 4l0z_A interface=27,89,117,118,121,124, vladhpgelvrtdspnflcsvlpthwRcnktlpiafkvvalgdvpdgtlvtvmagndenysaelrnataamknqvarfndlrfvgrsgRgksftltitvftnppqvatyhraikitVDgpRepRgslsfserlseleqlrrtamrvs > 4l0z_B interface=56,57,60,63,64, sgpiqlwqfllelltdkscqsfiswtgdgwefklsdpdevarrwgkrknkpkmnyEKlsRglRYyydkniihktagkryvyrfvcdlqsllgytpeelham
interface signature	RRVDRR/EKRRY

Estimated binding specificities ?

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# IC=12.653 IC/col=1.054 n_of_columns=12

specificity:

A |  81   0   0  96   6   0   0   0   0  10  12   5
C |   5   0   0   0   5   0   5   0   0  69   5   0
G |   5  96  96   0   5  96   0  96  96  12   5   6
T |   5   0   0   0  80   0  91   0   0   5  74  85

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updated Mon Jan 5 10:12:02 2026