4l0z_AB : 3D-footprint complex

structure name	CRYSTAL STRUCTURE OF RUNX1 AND ETS1 BOUND TO TCR ALPHA PROMOTER (CRYSTAL FORM 2)
reference	Leukemia 28 2040 2014
source	MUS MUSCULUS / HOMO SAPIENS
experiment	X-ray (resolution=2.70, R-factor=?)
structural superfamily	p53-like transcription factors;"Winged helix" DNA-binding domain;
reference complex	4l0y_A 4l18_B
links to other resources	NAKB PDIdb DNAproDB
protein sequence	> 4l0z_A interface=27,89,117,118,121,124, vladhpgelvrtdspnflcsvlpthwRcnktlpiafkvvalgdvpdgtlvtvmagndenysaelrnataamknqvarfndlrfvgrsgRgksftltitvftnppqvatyhraikitVDgpRepRgslsfserlseleqlrrtamrvs > 4l0z_B interface=56,57,60,63,64, sgpiqlwqfllelltdkscqsfiswtgdgwefklsdpdevarrwgkrknkpkmnyEKlsRglRYyydkniihktagkryvyrfvcdlqsllgytpeelham
interface signature	RRVDRR/EKRRY

Estimated binding specificities ?

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# IC=12.666 IC/col=1.055 n_of_columns=12

specificity:

A |  79   0   0  96   7   0   0   0   0  13  11   5
C |   5   0   0   0   0   0   5   0   0  67   7   7
G |   7  96  96   0   5  96   0  96  96  11   5   0
T |   5   0   0   0  84   0  91   0   0   5  73  84

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updated Wed Jul 30 02:04:34 2025