interface graph thumbnail
legend  pdf

structure nameSTRUCTURE OF KLF4 ZINC FINGER DNA BINDING DOMAIN IN COMPLEX WITH METHYLATED DNA
(Krueppel-like factor 4)
referenceOlanrewaju et al. 'Nucleic 42 4859 2014
sourceMus musculus
experimentX-ray (resolution=1.85, R-factor=0.189)
structural superfamilybeta-beta-alpha zinc fingers;
sequence familyZinc finger, C2H2 type;
reference complex2wbs_A
links to other resourcesNAKB PDBSum PDIdb DNAproDB
protein sequence
interface signatureKSHRSDRRSDH

Estimated binding specificities ?

readout + contactlogo
# IC=10.124 IC/col=1.012 n_of_columns=10 specificity:   
A |  14  82   0   0   7   0   7   0   7   0
C |  14   0   0   0  14   0   0   0   1  96
G |  51  14  96  96   7  96   0  96  81   0
T |  17   0   0   0  68   0  89   0   7   0
scan!

home
updated Sat Aug 2 06:59:23 2025