4mzr_ABCD : 3D-footprint complex

structure name	CRYSTAL STRUCTURE OF A POLYPEPTIDE P53 MUTANT BOUND TO DNA
reference	Halazonetis et al. J.Mol.Biol. 426 936 2014
source	Homo sapiens
experiment	X-ray (resolution=2.90, R-factor=?)
structural superfamily	p53-like transcription factors;p53 tetramerization domain;
reference complex	3q05_B
links to other resources	NAKB PDIdb DNAproDB
protein sequence	> 4mzr_A interface=155,184,187, sssvpsqktyqgsygfrlgflhsgtakfgtctyspalnkmfvqlaktvpvqlyvdstpppgtrvramaiykqsqhmtevvrrcphherssdsdglappqhlirvegnlraeylddpntfrhsvvvpyeppevgsdyttiyfkfmcnsscmggmnRrpilviitledssgnllgrdsfevrvcaCpgRdrrteeenlrkktmdgeyftlqirgrerfeqfrernealelkdaqat > 4mzr_B interface=27,28,155,183,184,187, sssvpsqktyqgsygfrlgflhsgtaKFgtctyspalnkmfvqlaktvpvqlyvdstpppgtrvramaiykqsqhmtevvrrcphherssdsdglappqhlirvegnlraeylddpntfrhsvvvpyeppevgsdyttiyfkfmcnsscmggmnRrpilviitledssgnllgrdsfevrvcACpgRdrrteeenlrkktmdgeyftlqirgrerfeqfrernealelkdaqat > 4mzr_C interface=27,28,184,187, sssvpsqktyqgsygfrlgflhsgtaKFgtctyspalnkmfvqlaktvpvqlyvdstpppgtrvramaiykqsqhmtevvrrcphherssdsdglappqhlirvegnlraeylddpntfrhsvvvpyeppevgsdyttiyfkfmcnsscmggmnrrpilviitledssgnllgrdsfevrvcaCpgRdrrteeenlrkktmdgeyftlqirgrerfeqfrernealelkdaqat > 4mzr_D interface=155,183,184,187, sssvpsqktyqgsygfrlgflhsgtakfgtctyspalnkmfvqlaktvpvqlyvdstpppgtrvramaiykqsqhmtevvrrcphherssdsdglappqhlirvegnlraeylddpntfrhsvvvpyeppevgsdyttiyfkfmcnsscmggmnRrpilviitledssgnllgrdsfevrvcACpgRdrrteeenlrkktmdgeyftlqirgrerfeqfrernealelkdaqat
interface signature	RCR/KFRACR/KFCR/RACR

Estimated binding specificities ?

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# IC=12.830 IC/col=0.916 n_of_columns=14

specificity:

A |   0  90  69   0   1   9  63   0  24   1   0  94  78   0
C |  96   1  11   0   4  65   0   0  24   1  96   1   6   0
G |   0   4   9  96   1   9   1  34  24  93   0   1   9  96
T |   0   1   7   0  90  13  32  62  24   1   0   0   3   0

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updated Wed Jun 24 22:02:30 2026