4oln_AB : 3D-footprint complex

structure name	ANCESTRAL STEROID RECEPTOR 1 IN COMPLEX WITH ESTROGEN RESPONSE ELEMENT DNA
reference	Ortlund et al. 'Cell(Cambridge,Mass.)' 159 58 2014
source	SYNTHETIC CONSTRUCT
experiment	X-ray (resolution=1.70, R-factor=?)
structural superfamily	Glucocorticoid receptor-like DNA-binding domain;
reference complex	4oln_B
links to other resources	NAKB PDIdb DNAproDB
protein sequence	> 4oln_A interface=24,27,28,31,32, kpkrlcqvcgdhasgfhygvwscEgcKAffKRsiqvdyvcpatnnctidkhrrkscqacrlrkclevgmt > 4oln_B interface=16,22,25,26,29,30, krlcqvcgdhasgfhYgvwscEgcKAffKRsiqdyvcpatnnctidkhrrkscqacrlrkclevgmt
interface signature	EKAKR/YEKAKR

Estimated binding specificities ?

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# IC=10.912 IC/col=0.839 n_of_columns=13

specificity:

A |   0   0   0   0  60  24  24  24  12   0  84   0   0
C |   0   0   0  96  12  24  24  24  12   0   0  96  96
G |  96  96   0   0  12  24  24  24  12  96  12   0   0
T |   0   0  96   0  12  24  24  24  60   0   0   0   0

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updated Wed Jul 30 02:29:13 2025