4oln_B : 3D-footprint complex

structure name	ANCESTRAL STEROID RECEPTOR 1 IN COMPLEX WITH ESTROGEN RESPONSE ELEMENT DNA (ANCSR1)
reference	Ortlund et al. 'Cell(Cambridge,Mass.)' 159 58 2014
source	SYNTHETIC CONSTRUCT
experiment	X-ray (resolution=1.70, R-factor=0.176)
structural superfamily	Glucocorticoid receptor-like DNA-binding domain;
sequence family	Zinc finger, C4 type two domains;
multimeric complexes	4oln_AB
links to other resources	NAKB PDIdb DNAproDB
protein sequence	> 4oln_B interface=16,22,25,26,29,30, krlcqvcgdhasgfhYgvwscEgcKAffKRsiqdyvcpatnnctidkhrrkscqacrlrkclevgmt
interface signature	YEKAKR

Estimated binding specificities ?

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# IC=2.653 IC/col=0.531 n_of_columns=5

specificity:

A |   7   2   6   9  42
C |   8   1  11  72  18
G |  64  89   5   6  18
T |  17   4  74   9  18

scan!

Dendrogram of similar interfaces ?

matrix format

  
  --EAKG--KTRG   L                            +4umm_A    
                                      +-------1 
  ----KGVG--RG   L                    !       +4tnt_B    
                     +----------------4 
  --ECKGAGKTRG   L   !                !      +4aa6_B    
                     !                +------2 
  ----KGVT--RG   L   !                       +5emc_A    
                   --7 
  --ECKGAGKGRG   L   !                       +1hcq_E    
                     !        +--------------3 
  --ECKGAGRG--   L   !   +----5              +4ond_A    
                     !   !    ! 
  ----KGVTRG--   L   +---6    +---------------2c7a_B    
                         ! 
  CAECKG--KGRG   L       +--------------------1cit_A

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updated Mon Jun 29 18:21:28 2026