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legend  pdf

structure nameANCESTRAL STEROID RECEPTOR 2 DBD HELIX MUTANT - ERE DNA COMPLEX
referenceOrtlund et al. 'Cell(Cambridge,Mass.)' 159 58 2014
sourcesynthetic construct
experimentX-ray (resolution=2.25, R-factor=?)
structural superfamilyGlucocorticoid receptor-like DNA-binding domain;
reference complex5cbz_E
links to other resourcesNAKB PDBSum PDIdb DNAproDB
protein sequence
interface signatureEKAR/EKAR

Estimated binding specificities ?

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# IC=8.695 IC/col=0.669 n_of_columns=13 specificity:   
A |   6   0   6   0  84  24  24  24   6  24  72   0   0
C |   6   0  12  96   6  24  24  24   6  24   6  96  96
G |   6  96   6   0   0  24  24  24   6  24  12   0   0
T |  78   0  72   0   6  24  24  24  78  24   6   0   0
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updated Wed Jul 30 02:29:58 2025