4ond_EF : 3D-footprint complex

structure name	ANCESTRAL STEROID RECEPTOR 2 DBD HELIX MUTANT - ERE DNA COMPLEX
reference	Ortlund et al. 'Cell(Cambridge,Mass.)' 159 58 2014
source	synthetic construct
experiment	X-ray (resolution=2.25, R-factor=?)
structural superfamily	Glucocorticoid receptor-like DNA-binding domain;
reference complex	5cbz_E
links to other resources	NAKB PDIdb DNAproDB
protein sequence	> 4ond_E interface=22,25,26,30, qkvclicgdeasgchygvltcEgcKAffkRavegqhnylcagrndciidkirrkncpacrlrkclqagmtl > 4ond_F interface=22,25,26,30, qkvclicgdeasgchygvltcEgcKAffkRavegqhnylcagrndciidkirrkncpacrlrkclqagmtl
interface signature	EKAR/EKAR

Estimated binding specificities ?

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# IC=10.444 IC/col=0.746 n_of_columns=14

specificity:

A |   3   0   6  17  96  24  24  24   0  16  92   3   6   0
C |   6   0   3  62   0  24  24  24   0  11   0  90  84   3
G |  84  96   3   3   0  24  24  24   0  66   3   3   3  16
T |   3   0  84  14   0  24  24  24  96   3   1   0   3  77

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updated Mon Sep 9 23:16:38 2024