4oo8_D : 3D-footprint complex

structure name	CRYSTAL STRUCTURE OF STREPTOCOCCUS PYOGENES CAS9 IN COMPLEX WITH GUIDE RNA AND TARGET DNA (CRISPR-associated endonuclease Cas9Csn1)
reference	Nishimasu et al. 'Cell(Cambridge,Mass.)' 156 935 2014
source	Streptococcus pyogenes serotype M1
experiment	X-ray (resolution=2.50, R-factor=0.224)
multimeric complexes	7v59_BE
reference complex	6vpc_F
links to other resources	NAKB PDIdb DNAproDB
protein sequence	> 4oo8_D interface=70,445,448,493,586,692,909,910, kkysiglaigtnsvgwavitdeykvpskkfkvlgntdrhsikknligallfdsgetaeatrlkrtarrrYtrrknrilylqeifsnemakvddsffhrleesflveedkkherhpifgnivdevayhekyptiyhlrkklvdstdkadlrliylalahmikfrghfliegdlnpdnsdvdklfiqlvqtynqlfeenpinasgvdakailsarlsksrrlenliaqlpgekknglfgnlialslgltpnfksnfdlaedaklqlskdtydddldnllaqigdqyadlflaaknlsdaillsdilrvnteitkaplsasmikrydehhqdltllkalvrqqlpekykeiffdqskngyagyidggasqeefykfikpilekmdgteellvklnredllrkqrtfdngsiphqihlgelhailrrqedfypflkdnrekiekiltfRipYyvgplargnsrfawmtrkseetitpwnfeevvdkgasaqsfierMtnfdknlpnekvlpkhsllyeyftvyneltkvkyvtegmrkpaflsgeqkkaivdllfktnrkvtvkqlkedyfkkieefdsveisgvedrfNaslgtyhdllkiikdkdfldneenediledivltltlfedremieerlktyahlfddkvmkqlkrrrytgwgrlsrklingirdkqsgktildflksdgfanrnfMqlihddsltfkediqkaqvdslhehianlagspaikkgilqtvkvvdelvkvmgrhkpeniviemarrqlvetrqitkhvaqildsrmntkydendklirevkvitlksklvsdfrkdfqfykvreinnyhhahdaylnavvgtalikkypklesefvygdfysnimnffklietngetgeivwdkgrdfatvrkvlsmpqvnivkktevqtggfsKEsilpkrnsdkliarkkdwdpkkyggfdsptvaysvlvvakvekgkskklksvkellgitimerssfeknpidfleakgykevkkdliiklpkyslfelengrkrmlasagelqkgnelalpskyvnflylashyepedneqkqlfveqhkhyldeiieqisefskrviladanldkvlsaynkhrdkpireqaeniihlftltnlgapaafkyfdttidrkrytstkevldatlihqsitglyetridlsqlg
interface signature	YRYMNMKE

Estimated binding specificities ?

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# IC=6.247 IC/col=0.297 n_of_columns=21

specificity:

A |   7  73   0  24  24  24  24   7   7   0  24  24  24  24  24  24  24  24  24  24   0
C |  73   7   0  24  24  24  24   9  73   0  24  24  24  24  24  24  24  24  24  24  96
G |   7   9  96  24  24  24  24  73   9  96  24  24  24  24  24  24  24  24  24  24   0
T |   9   7   0  24  24  24  24   7   7   0  24  24  24  24  24  24  24  24  24  24   0

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updated Fri Jan 9 01:23:53 2026