4oor_AB : 3D-footprint complex

structure name	ANCESTRAL STEROID RECEPTOR 2 DNA BINDING DOMAIN IN COMPLEX WITH A STEROID RESPONSE ELEMENT
reference	Ortlund et al. 'Cell(Cambridge,Mass.)' 159 58 2014
source	synthetic construct
experiment	X-ray (resolution=2.70, R-factor=?)
structural superfamily	Glucocorticoid receptor-like DNA-binding domain;
reference complex	4ond_A
links to other resources	NAKB PDIdb DNAproDB
protein sequence	> 4oor_A interface=26,27,31, pqkvclicgdeasgchygvltcgscKVffkRavegqhnylcagrndciidkirrkncpacrlrkclqagmtlg > 4oor_B interface=24,25,29, kvclicgdeasgchygvltcgscKVffkRavegqhnylcagrndciidkirrkncpacrlrkclqagmtl
interface signature	KVR/KVR

Estimated binding specificities ?

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# IC=6.478 IC/col=0.498 n_of_columns=13

specificity:

A |   1  24  48   0  96  24  24  24   0   0  24  24  67
C |   0  24   9  96   0  24  24  24   0   0  24  24  11
G |  76  24  28   0   0  24  24  24   9  96  24  24   9
T |  19  24  11   0   0  24  24  24  87   0  24  24   9

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updated Mon Jan 5 10:41:17 2026