4oor_AB : 3D-footprint complex

structure name	ANCESTRAL STEROID RECEPTOR 2 DNA BINDING DOMAIN IN COMPLEX WITH A STEROID RESPONSE ELEMENT
reference	Ortlund et al. 'Cell(Cambridge,Mass.)' 159 58 2014
source	synthetic construct
experiment	X-ray (resolution=2.70, R-factor=?)
structural superfamily	Glucocorticoid receptor-like DNA-binding domain;
reference complex	5cbz_E
links to other resources	NAKB PDIdb DNAproDB
protein sequence	> 4oor_A interface=26,27,31, pqkvclicgdeasgchygvltcgscKVffkRavegqhnylcagrndciidkirrkncpacrlrkclqagmtlg > 4oor_B interface=24,25,29, kvclicgdeasgchygvltcgscKVffkRavegqhnylcagrndciidkirrkncpacrlrkclqagmtl
interface signature	KVR/KVR

Estimated binding specificities ?

readout + contact

# IC=6.265 IC/col=0.482 n_of_columns=13

specificity:

A |   6  24  24   0  82  24  24  24   0   0  54  24   6
C |  16  24  24  96   6  24  24  24   0   0  13  24  84
G |  13  24  24   0   6  24  24  24   0  96  13  24   0
T |  61  24  24   0   2  24  24  24  96   0  16  24   6

scan!

home
updated Mon Sep 9 23:16:48 2024