4oor_AB : 3D-footprint complex

structure name	ANCESTRAL STEROID RECEPTOR 2 DNA BINDING DOMAIN IN COMPLEX WITH A STEROID RESPONSE ELEMENT
reference	Ortlund et al. 'Cell(Cambridge,Mass.)' 159 58 2014
source	synthetic construct
experiment	X-ray (resolution=2.70, R-factor=?)
structural superfamily	Glucocorticoid receptor-like DNA-binding domain;
reference complex	5cbz_E
links to other resources	NAKB PDIdb DNAproDB
protein sequence	> 4oor_A interface=26,27,31, pqkvclicgdeasgchygvltcgscKVffkRavegqhnylcagrndciidkirrkncpacrlrkclqagmtlg > 4oor_B interface=24,25,29, kvclicgdeasgchygvltcgscKVffkRavegqhnylcagrndciidkirrkncpacrlrkclqagmtl
interface signature	KVR/KVR

Estimated binding specificities ?

readout + contact

# IC=6.472 IC/col=0.498 n_of_columns=13

specificity:

A |   1  24  17   0  96  24  24  24   8   0  24  24  69
C |   0  24   8  96   0  24  24  24  10   0  24  24   8
G |  87  24  17   0   0  24  24  24   0  96  24  24   8
T |   8  24  54   0   0  24  24  24  78   0  24  24  11

scan!

home
updated Fri Dec 13 21:00:31 2024