4oor_AB : 3D-footprint complex

structure name	ANCESTRAL STEROID RECEPTOR 2 DNA BINDING DOMAIN IN COMPLEX WITH A STEROID RESPONSE ELEMENT
reference	Ortlund et al. 'Cell(Cambridge,Mass.)' 159 58 2014
source	synthetic construct
experiment	X-ray (resolution=2.70, R-factor=?)
structural superfamily	Glucocorticoid receptor-like DNA-binding domain;
reference complex	4tnt_B
links to other resources	NAKB PDIdb DNAproDB
protein sequence	> 4oor_A interface=26,27,31, pqkvclicgdeasgchygvltcgscKVffkRavegqhnylcagrndciidkirrkncpacrlrkclqagmtlg > 4oor_B interface=24,25,29, kvclicgdeasgchygvltcgscKVffkRavegqhnylcagrndciidkirrkncpacrlrkclqagmtl
interface signature	KVR/KVR

Estimated binding specificities ?

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# IC=6.378 IC/col=0.491 n_of_columns=13

specificity:

A |   6  24  24   0  78  24  24  24   0   0  64  24  13
C |   6  24  24  96   6  24  24  24   0   0  13  24  75
G |   9  24  24   0   6  24  24  24   0  96   6  24   0
T |  75  24  24   0   6  24  24  24  96   0  13  24   8

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updated Wed Jun 24 22:18:40 2026