4ov7_AB : 3D-footprint complex

structure name	ANCESTRAL STEROID RECEPTOR 2 DBD HELIX MUTANT - SRE DNA COMPLEX
reference	'Cell(Cambridge,Mass.)' 159 58 2014 X-RAY DIFFRACTION
source	synthetic construct
experiment	X-ray (resolution=2.70, R-factor=?)
structural superfamily	Glucocorticoid receptor-like DNA-binding domain;
reference complex	5cbz_E
links to other resources	NAKB PDIdb DNAproDB
protein sequence	> 4ov7_A interface=26,27,31, pqkvclicgdeasgchygvltcgscKVffkRavegqhnylcagrndciidkirrkncpacrlrkclqagmtlg > 4ov7_B interface=24,25,29, kvclicgdeasgchygvltcgscKVffkRavegqhnylcagrndciidkirrkncpacrlrkclqagmtl
interface signature	KVR/KVR

Estimated binding specificities ?

readout + contact

# IC=6.294 IC/col=0.484 n_of_columns=13

specificity:

A |  16  24  24   0  75  24  24  24   0   0  64  24   6
C |   6  24  24  96   6  24  24  24   0   0   6  24  82
G |   6  24  24   0   9  24  24  24   0  96  13  24   2
T |  68  24  24   0   6  24  24  24  96   0  13  24   6

scan!

home
updated Wed Jul 30 02:32:30 2025