4ov7_AB : 3D-footprint complex

structure name	ANCESTRAL STEROID RECEPTOR 2 DBD HELIX MUTANT - SRE DNA COMPLEX
reference	'Cell(Cambridge,Mass.)' 159 58 2014 X-RAY DIFFRACTION
source	synthetic construct
experiment	X-ray (resolution=2.70, R-factor=?)
structural superfamily	Glucocorticoid receptor-like DNA-binding domain;
reference complex	5cbz_E
links to other resources	NAKB PDIdb DNAproDB
protein sequence	> 4ov7_A interface=26,27,31, pqkvclicgdeasgchygvltcgscKVffkRavegqhnylcagrndciidkirrkncpacrlrkclqagmtlg > 4ov7_B interface=24,25,29, kvclicgdeasgchygvltcgscKVffkRavegqhnylcagrndciidkirrkncpacrlrkclqagmtl
interface signature	KVR/KVR

Estimated binding specificities ?

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# IC=6.480 IC/col=0.498 n_of_columns=13

specificity:

A |   1  24  17   0  96  24  24  24   8   0  24  24  69
C |   0  24  17  96   0  24  24  24   8   0  24  24   8
G |  87  24  10   0   0  24  24  24   0  96  24  24   8
T |   8  24  52   0   0  24  24  24  80   0  24  24  11

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updated Fri Dec 13 21:02:51 2024