4ov7_EF : 3D-footprint complex

structure name	ANCESTRAL STEROID RECEPTOR 2 DBD HELIX MUTANT - SRE DNA COMPLEX
reference	'Cell(Cambridge,Mass.)' 159 58 2014 X-RAY DIFFRACTION
source	synthetic construct
experiment	X-ray (resolution=2.70, R-factor=?)
structural superfamily	Glucocorticoid receptor-like DNA-binding domain;
reference complex	5cbz_E
links to other resources	NAKB PDIdb DNAproDB
protein sequence	> 4ov7_E interface=26,27,31, pqkvclicgdeasgchygvltcgscKVffkRavegqhnylcagrndciidkirrkncpacrlrkclqagmtl > 4ov7_F interface=25,26,30, qkvclicgdeasgchygvltcgscKVffkRaveghnylcagrndciidkirrkncpacrlrkclqagmtl
interface signature	KVR/KVR

Estimated binding specificities ?

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# IC=7.849 IC/col=0.561 n_of_columns=14

specificity:

A |   0  24  69   0  96  24  24  24   0   0  10  24  24  61
C |   0  24   0  96   0  24  24  24   0   0  26  24  24   0
G |  96  24  19   0   0  24  24  24   0  96  17  24  24  18
T |   0  24   8   0   0  24  24  24  96   0  43  24  24  17

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updated Wed Jul 30 02:32:41 2025