4plb_BD : 3D-footprint complex

structure name	CRYSTAL STRUCTURE OF S.A. GYRASE-AM8191 COMPLEX
reference	Soisson et al. 'Acs 5 609 2014
source	STAPHYLOCOCCUS AUREUS
experiment	X-ray (resolution=2.69, R-factor=?)
structural superfamily	Type II DNA topoisomerase;
reference complex	5iwi_C
links to other resources	NAKB PDIdb DNAproDB
protein sequence	> 4plb_B interface=42,44,266,273,303,356, kladcsskspeeceiflvegdsaggstksgrdsrtqailplRgKilnvekarldrilnnneirqmitafgtgiggdfdlakaryhkivimtdadvdgahirtllltffyrfmrplieagyvyiaqpptgykglgemnadqlwettmnpehrallqvkledaieadqtfemlmgdvvenrrqfiednavyanernitsemresfldyamsvivaralpdvrdglkpvhrrilyglneqgmtpdksykksarivgdvmgkyhphgdsSiyeamvRmaqdfsyryplvdgqgnfgsmdgdgaaamRftearmtkitlellrdinkdtidfidnydgnerepsvlparfpnllangasgIavgmatnipphnltelingvlslsknpdisiaelmediegpdfptaglilgksgirrayetgrgsiqmrsravieergggrqrivvteipfqvnkarmiekiaelvrdkkidgitdlrdetslrtgvrvvidvrkdanasvilnnlykqtplqtsfgvnmialvngrpklinlkealvhylehqktvvrrrtqynlrkakdrahileglrialdhideiistiresdtdkvameslqqrfklsekqaqaildmrlrrltglerdkieaeynellnyiseletiladeevllqlvrdelteirdrfgddrrteiqlg > 4plb_D interface=42,44,213,265,302,355, kladcsskspeeceiflvegdsaggstksgrdsrtqailplRgKilnvekarldrilnnneirqmitafgtgiggdfdlakaryhkivimtdadvdgahirtllltffyrfmrplieagyvyiaqpptgykglgemnadqlwettmnpehrallqvkledaieadqtfemlmgdvvenrrqfiednavynernitsemresfldyamsvivaRalpdvrdglkpvhrrilyglneqgmtpdksykksarivgdvmgkyhphgdsSiyeamvrmaqdfsyryplvdgqgnfgsmdgdgaaamRftearmtkitlellrdinkdtidfidnydgnerepsvlparfpnllangasgIavgmatnipphnltelingvlslsknpdisiaelmediegpdfptaglilgksgirrayetgrgsiqmrsravieergggrqrivvteipfqvnkarmiekiaelvrdkkidgitdlrdetslrtgvrvvidvrkdanasvilnnlykqtplqtsfgvnmialvngrpklinlkealvhylehqktvvrrrtqynlrkakdrahileglrialdhideiistiresdtdkvameslqqrfklsekqaqaildmrlrrltglerdkieaeynellnyiseletiladeevllqlvrdelteirdrfgddrrteiql
interface signature	RKSRRI/RKRSRI

Estimated binding specificities ?

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# IC=10.419 IC/col=0.744 n_of_columns=14

specificity:

A |   0   0  24  87  10  10  11  24  10   3   0  24   0   0
C |  96   0  24   3  13  13  10  24  76  87   0  24  96   0
G |   0  96  24   3  60  67  65  24  10   3   0  24   0  96
T |   0   0  24   3  13   6  10  24   0   3  96  24   0   0

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updated Wed Jun 24 22:23:32 2026