4r2e_A : 3D-footprint complex

structure name	WILMS TUMOR PROTEIN (WT1) ZINC FINGERS IN COMPLEX WITH METHYLATED DNA (Wilms tumor protein, isoform 4CRA_a)
reference	Olanrewaju et al. 'Genes 28 2304 2014
source	Homo sapiens
experiment	X-ray (resolution=1.84, R-factor=0.164)
structural superfamily	beta-beta-alpha zinc fingers;
sequence family	Zinc finger, C2H2 type;
links to other resources	NAKB PDIdb DNAproDB
protein sequence	> 4r2e_A interface=17,19,20,23,45,46,47,48,51,75,76,77,78,81, ekpyqcdfkdcerrfsRsDQlkRhqrrhtgvkpfqcktcqrkfsRSDHlkThtrthtgekpfscrwpscqkkfaRSDElvRhhnmhqr
interface signature	RDQRRSDHTRSDER

Estimated binding specificities ?

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# IC=7.093 IC/col=0.709 n_of_columns=10

specificity:

A |   9   2   8   0   2   1   0  24  24  14
C |   9  92   8   0   4   1   0  24  24  14
G |  67   1  70   0  88  93  96  24  24  16
T |  11   1  10  96   2   1   0  24  24  52

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updated Tue Dec 17 00:13:16 2024