4r2e_A : 3D-footprint complex

structure name	WILMS TUMOR PROTEIN (WT1) ZINC FINGERS IN COMPLEX WITH METHYLATED DNA (Wilms tumor protein, isoform 4CRA_a)
reference	Olanrewaju et al. 'Genes 28 2304 2014
source	Homo sapiens
experiment	X-ray (resolution=1.84, R-factor=0.164)
structural superfamily	beta-beta-alpha zinc fingers;
sequence family	Zinc finger, C2H2 type;
reference complex	5kl3_A
links to other resources	NAKB PDIdb DNAproDB
protein sequence	> 4r2e_A interface=17,19,20,23,45,46,47,48,51,75,76,77,78,81, ekpyqcdfkdcerrfsRsDQlkRhqrrhtgvkpfqcktcqrkfsRSDHlkThtrthtgekpfscrwpscqkkfaRSDElvRhhnmhqr
interface signature	RDQRRSDHTRSDER

Estimated binding specificities ?

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# IC=9.064 IC/col=0.906 n_of_columns=10

specificity:

A |   8   8  24   0   0   0  72   0   8   0
C |  72  72  24  96  96  88   8  96   0  96
G |   8   8  24   0   0   0   8   0  88   0
T |   8   8  24   0   0   8   8   0   0   0

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updated Sat Aug 2 07:12:52 2025