interface graph thumbnail
legend  pdf

structure nameWILMS TUMOR PROTEIN (WT1) ZINC FINGERS IN COMPLEX WITH METHYLATED DNA
(Wilms tumor protein, isoform 4CRA_a)
referenceOlanrewaju et al. 'Genes 28 2304 2014
sourceHomo sapiens
experimentX-ray (resolution=1.84, R-factor=0.164)
structural superfamilybeta-beta-alpha zinc fingers;
sequence familyZinc finger, C2H2 type;
reference complex5kl3_A
links to other resourcesNAKB PDBSum PDIdb DNAproDB
protein sequence
interface signatureRDQRRSDHTRSDER

Estimated binding specificities ?

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# IC=7.093 IC/col=0.709 n_of_columns=10 specificity:   
A |   9   2   8   0   2   1   0  24  24  14
C |   9  92   8   0   4   1   0  24  24  14
G |  67   1  70   0  88  93  96  24  24  16
T |  11   1  10  96   2   1   0  24  24  52
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updated Thu Sep 12 20:01:48 2024