interface graph thumbnail
legend  pdf

structure nameWILMS TUMOR PROTEIN (WT1) ZINC FINGERS IN COMPLEX WITH HYDROXYMETHYLATED DNA
(Wilms tumor protein, isoform 4CRA_a)
referenceOlanrewaju et al. 'Genes 28 2304 2014
sourceHomo sapiens
experimentX-ray (resolution=1.79, R-factor=0.180)
structural superfamilybeta-beta-alpha zinc fingers;
sequence familyZinc finger, C2H2 type;
reference complex5kl3_A
links to other resourcesNAKB PDBSum PDIdb DNAproDB
protein sequence
interface signatureRDQRRSDHTRSDER

Estimated binding specificities ?

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# IC=9.764 IC/col=1.085 n_of_columns=9 specificity:   
A |  13   0   0   0   0   0   0   0  13
C |  13  96   0   0   0   0   0   0  16
G |  54   0  96   0  96  96  96  96  13
T |  16   0   0  96   0   0   0   0  54
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updated Thu Sep 12 20:01:53 2024