interface graph thumbnail
legend  pdf

structure nameWILMS TUMOR PROTEIN (WT1) Q369P ZINC FINGERS IN COMPLEX WITH METHYLATED DNA
(Wilms tumor protein, isoform 4CRA_a)
referenceOlanrewaju et al. 'Genes 28 2304 2014
sourceHomo sapiens
experimentX-ray (resolution=2.49, R-factor=0.210)
structural superfamilybeta-beta-alpha zinc fingers;
sequence familyZinc finger, C2H2 type;
reference complex5kl3_A
links to other resourcesNAKB PDBSum PDIdb DNAproDB
protein sequence
interface signatureRDRRDHTRDER

Estimated binding specificities ?

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# IC=5.794 IC/col=0.579 n_of_columns=10 specificity:   
A |   4   9   4  10  22   0   1  24  12  28
C |   4  60   3  12   3   0   1  25  12  17
G |  83  14  86  12  68  96  91  26  60  13
T |   5  13   3  62   3   0   3  21  12  38
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updated Thu Sep 12 20:02:01 2024