4r2s_A : 3D-footprint complex

structure name	WILMS TUMOR PROTEIN (WT1) Q369P ZINC FINGERS IN COMPLEX WITH METHYLATED DNA (Wilms tumor protein, isoform 4CRA_a)
reference	Olanrewaju et al. 'Genes 28 2304 2014
source	Homo sapiens
experiment	X-ray (resolution=2.49, R-factor=0.210)
structural superfamily	beta-beta-alpha zinc fingers;
sequence family	Zinc finger, C2H2 type;
reference complex	5kl3_A
links to other resources	NAKB PDIdb DNAproDB
protein sequence	> 4r2s_A interface=18,20,24,46,48,49,52,76,78,79,82, sekpyqcdfkdcerrfsRsDplkRhqrrhtgvkpfqcktcqrkfsRsDHlkThtrthtgekpfscrwpscqkkfaRsDElvRhhnmhqr
interface signature	RDRRDHTRDER

Estimated binding specificities ?

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# IC=5.769 IC/col=0.577 n_of_columns=10

specificity:

A |   4   9   4  10  21   0   1  24  12  27
C |   4  60   3  12   3   0   1  25  12  17
G |  83  14  86  12  68  96  91  26  60  14
T |   5  13   3  62   4   0   3  21  12  38

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updated Fri Jan 9 01:33:14 2026