4r2s_A : 3D-footprint complex

structure name	WILMS TUMOR PROTEIN (WT1) Q369P ZINC FINGERS IN COMPLEX WITH METHYLATED DNA (Wilms tumor protein, isoform 4CRA_a)
reference	Olanrewaju et al. 'Genes 28 2304 2014
source	Homo sapiens
experiment	X-ray (resolution=2.49, R-factor=0.210)
structural superfamily	beta-beta-alpha zinc fingers;
sequence family	Zinc finger, C2H2 type;
reference complex	5kl3_A
links to other resources	NAKB PDIdb DNAproDB
protein sequence	> 4r2s_A interface=18,20,24,46,48,49,52,76,78,79,82, sekpyqcdfkdcerrfsRsDplkRhqrrhtgvkpfqcktcqrkfsRsDHlkThtrthtgekpfscrwpscqkkfaRsDElvRhhnmhqr
interface signature	RDRRDHTRDER

Estimated binding specificities ?

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# IC=7.621 IC/col=0.762 n_of_columns=10

specificity:

A |  56  24  24   4   0   0  96   7   0   9
C |  13  24  24  88  96  96   0  74   0  69
G |  13  24  24   2   0   0   0   7  96   9
T |  14  24  24   2   0   0   0   8   0   9

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updated Sat Aug 2 07:13:09 2025