4tnt_AB : 3D-footprint complex

structure name	STRUCTURE OF THE HUMAN MINERALOCORTICOID RECEPTOR IN COMPLEX WITH DNA
reference	Ortlund et al. 'Plos 9 e107000 2014
source	Homo sapiens
experiment	X-ray (resolution=2.39, R-factor=?)
structural superfamily	Glucocorticoid receptor-like DNA-binding domain;
reference complex	4tnt_B
links to other resources	NAKB PDIdb DNAproDB
protein sequence	> 4tnt_A interface=25,26,30, skiclvcgdeasgchygvvtcgscKVffkRavegqhnylcagrndciidkirrkncpacrlqkclqagmnlg > 4tnt_B interface=25,26,30, skiclvcgdeasgchygvvtcgscKVffkRavegqhnylcagrndciidkirrkncpacrlqkclqagmnlg
interface signature	KVR/KVR

Estimated binding specificities ?

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# IC=6.586 IC/col=0.507 n_of_columns=13

specificity:

A |   9  24  24   0  72  24  24  24  11   0   8  24   0
C |   0  24  24  96   8  24  24  24   8   0   8  24  96
G |  87  24  24   0   8  24  24  24   8  96   8  24   0
T |   0  24  24   0   8  24  24  24  69   0  72  24   0

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updated Wed Jul 30 02:53:24 2025