4xrm_AB : 3D-footprint complex

structure name	HOMODIMER OF TALE TYPE HOMEOBOX TRANSCRIPTION FACTOR MEIS1 COMPLEXES WITH SPECIFIC DNA
reference	Morgunova et al. Nature 527 384 2015
source	Homo sapiens
experiment	X-ray (resolution=1.60, R-factor=?)
structural superfamily	Homeodomain-like;
reference complex	4xrm_B
links to other resources	NAKB PDIdb DNAproDB
protein sequence	> 4xrm_A interface=44,47,48,51,52, ifpkvatnimrawlfqhlthpypseeqkkqlaqdtgltilqvnNwfINarRRivqpmid > 4xrm_B interface=47,50,51,54,55, smgifpkvatnimrawlfqhlthpypseeqkkqlaqdtgltilqvnNwfINarRRivqpmidqs
interface signature	NINRR/NINRR

Estimated binding specificities ?

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# IC=12.472 IC/col=1.039 n_of_columns=12

specificity:

A |   5   0  96   0  80  81   6   5   0   0   0  80
C |   5   0   0  96   6   5   5   6   0   0  96   6
G |   5  96   0   0   5   5   5   5  96   0   0   5
T |  81   0   0   0   5   5  80  80   0  96   0   5

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updated Mon Jan 5 12:03:50 2026