4xrm_AB : 3D-footprint complex

structure name	HOMODIMER OF TALE TYPE HOMEOBOX TRANSCRIPTION FACTOR MEIS1 COMPLEXES WITH SPECIFIC DNA
reference	Morgunova et al. Nature 527 384 2015
source	Homo sapiens
experiment	X-ray (resolution=1.60, R-factor=?)
structural superfamily	Homeodomain-like;
reference complex	4xrm_B
links to other resources	NAKB PDIdb DNAproDB
protein sequence	> 4xrm_A interface=44,47,48,51,52, ifpkvatnimrawlfqhlthpypseeqkkqlaqdtgltilqvnNwfINarRRivqpmid > 4xrm_B interface=47,50,51,54,55, smgifpkvatnimrawlfqhlthpypseeqkkqlaqdtgltilqvnNwfINarRRivqpmidqs
interface signature	NINRR/NINRR

Estimated binding specificities ?

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# IC=12.734 IC/col=1.061 n_of_columns=12

specificity:

A |   6   0  96   0  78  90   6   6   0   0   0  78
C |   6   0   0  96   6   0   6   6   0   0  96   6
G |   6  96   0   0   6   6   0   6  96   0   0   6
T |  78   0   0   0   6   0  84  78   0  96   0   6

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updated Wed Jul 30 03:42:41 2025