structure name | HOMODIMER OF TALE TYPE HOMEOBOX TRANSCRIPTION FACTOR MEIS1 COMPLEXES WITH SPECIFIC DNA (Homeobox protein Meis2) |
reference | Morgunova et al. Nature 527 384 2015 |
source | Homo sapiens |
experiment | X-ray (resolution=1.60, R-factor=0.177) |
structural superfamily | Homeodomain-like; |
sequence family | Homeobox domain 28; |
multimeric complexes | 4xrm_AB 4xrs_BI 5eg0_AB 5ego_AB |
redundant complexes | 5bng_B 5eg0_A 4xrs 5ego |
links to other resources | NAKB PDIdb DNAproDB |
protein sequence | |
interface signature | NINRR |
Estimated binding specificities ?
readout + contact |
A | 9 0 96 0 67 69 C | 9 0 0 96 11 9 G | 11 96 0 0 9 9 T | 67 0 0 0 9 9scan! |
Related DNA sequences reported in the literature ?
site | source | matches (E-value) |
---|---|---|
term: MEIS1 | ||
TGACAG | PubMed | 4xrm_B(8.80e-07), 4xrm_AB(1.60e-04), 5eg0_AB(2.61e-04), ... (total=5) |
CCAAT | PubMed | 4xrm_AB(7.13e-03) |
TGATTGAC | PubMed | 4xrm_B(6.36e-03) |
Dendrogram of similar interfaces ?
matrix formatRT--------ITQCNAMC-- L +-----------------------------2r5y_A +-2 ----------VA--NAQART L ! ! +-1o4x_A --3 +---------------------------1 ----------VTCCNAQART L ! +-8g87_X ! --DTRTRGTTKT-------- L +-----------------------------2o8k_A |
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updated Fri Sep 13 18:58:45 2024