Estimated binding specificities ?

structure nameCRYSTAL STRUCTURE OF HUMAN TDP-43 RRM1 DOMAIN WITH D169G MUTATION IN COMPLEX WITH AN UNMODIFIED SINGLE-STRANDED DNA
(TAR DNA-binding protein 43)
referenceChiang et al. 'Sci 6 21581 2016
sourceHomo sapiens
experimentX-ray (resolution=3.00, R-factor=0.275)
structural superfamilyRNA-binding domain, RBD;
sequence familyRNA recognition motif aka RRM, RBD, or;
reference complex4y0f_A
links to other resourcesNAKB PDBSum PDIdb DNAproDB
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# IC=6.713 IC/col=1.119 n_of_columns=6 specificity:   
A |   0   0  38   0   0   0
C |   0   0  19   0  96   0
G |   0  96  19  96   0  96
T |  96   0  20   0   0   0
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updated Thu Sep 12 20:17:47 2024