4y5w_AC : 3D-footprint complex

structure name	TRANSCRIPTION FACTOR-DNA COMPLEX
reference	Ouyang et al. Proc.Natl.Acad.Sci.USA 113 13015 2016
source	Homo sapiens
experiment	X-ray (resolution=3.10, R-factor=?)
structural superfamily	p53-like transcription factors;SH2 domain;STAT;
reference complex	4y5w_B
links to other resources	NAKB PDIdb DNAproDB
protein sequence	> 4y5w_A interface=203,241,242,244,245, kfktglrrlqhrvgeihllrealqkalamllqettgeleaakalvlkriqiwkrqqqlagngapfeeslaplqerceslvdiysqlqqevgaaggetrasltgrldevlrtlvtscflvekqppqvlktqtkfqagvrfllglrflgpakpplvradmvtekqaretgeiinntvplensipgnccsalfknlllkkikrceRkgtesvteekcavlfsasftlglpiqlqalslplvviVHgNQdnnakatilwdnafsemdrvpfvvaervpwekmcetlnlkfmaevgtnrgllpehflflaqkifndnslsmeafqhrsvswsqfnkeillgrgftfwqwfdgvldltkrclrsywsdrliigfiskqyvtslllnepdgtfllrfsdseiggitiahvirgqdgspqieniqpfsakdlsirslgdrirdlaqlknlypkkpkdeafrshykpeqmgkdgrgvpatikmtve > 4y5w_C interface=127,234,235, kfktglrrlqhrvgeihllrealqkealamllqettgeleaakalvlkriqiwkrqqqlagngapfeeslaplqerceslvdiysqlqqevgaagtrasltgrldevlrtlvtscflvekqppqvlKtqtkfqagvrfllglrflgapakpplvradmvtekqaretgeiinntvplensipgnccsalfknlllkkikrcsvteekcavlfsasftlgpiqlqalslplvviVHgnqdnnakatilwdnafsemdrvpfvvaervpwekmcetlnlkfmaevgtnrgllpehflflaqkifndnslsmeafqhrsvswsqfnkeillgrgftfwqwfdgvldltkrclrsywsdrliigfiskqyvtslllnepdgtfllrfsdseiggitiahvigspqieniqpfsakdlsirslgdrirdlaqlknlypkkpkdeafrshykpeqmggrgvpatikmtve
interface signature	RVHNQ/KVH

Estimated binding specificities ?

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# IC=6.549 IC/col=0.468 n_of_columns=14

specificity:

A |   0   8  24  24   0   0  96  69  24  24  24  24  24  72
C |  96  69  24  24   0   0   0   8  24  24  24  24  24   8
G |   0  11  24  24  96  88   0  11  24  24  24  24  24   8
T |   0   8  24  24   0   8   0   8  24  24  24  24  24   8

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updated Mon Jan 5 12:15:59 2026