| structure name | TRANSCRIPTION FACTOR-DNA COMPLEX (Signal transducer and activator of transcription 6) |
| reference | Ouyang et al. Proc.Natl.Acad.Sci.USA 113 13015 2016 |
| source | Homo sapiens |
| experiment | X-ray (resolution=3.10, R-factor=0.251) |
| structural superfamily | p53-like transcription factors;SH2 domain;STAT; |
| sequence family | STAT protein, DNA binding domain; STAT protein, allalpha domain; SH2 domain; |
| multimeric complexes | 4y5w_AC 4y5w_BD 5d39_AC 5d39_BD |
| redundant complexes |  5d39_B
|
| links to other resources | NAKB  PDIdb DNAproDB |
| protein sequence |
No structural evidence for specific binding to DNA (<4 informative columns)
Related DNA sequences reported in the literature ?
| site | source | matches (E-value) |
|---|---|---|
| term: STAT6 | ||
| CTTCNNNGAAG | PubMed | 5d39_AC(1.50e-04), 5d39_BD(1.51e-04) |
| TTCCNNGGAA | PubMed | 4y5w_AC(2.12e-03), 5d39_AC(3.94e-04), 5d39_BD(3.98e-04), ... (total=4) |
| TTTCNNNGAAA | PubMed | 5d39_AC(1.50e-04), 5d39_BD(1.51e-04) |
| ATTCCTAGAAAG | PubMed | 5d39_AC(6.33e-06), 5d39_BD(5.47e-09), 5d39_B(7.18e-03) |
Dendrogram of similar interfaces ?
matrix format----KA--VTHG--NTQT L +------4y5w_B +----------------2 KCEC----STNTVGSTQT L ! ! +1bf5_A --3 +-----1 --------STNT----QT ! +1bg1_A ! RG----RTVCDC----RG L +-----------------------3wu1_A |
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updated Sun Aug 3 08:41:51 2025