interface graph thumbnail
legend  pdf

structure nameTRANSCRIPTION FACTOR-DNA COMPLEX
referenceOuyang et al. Proc.Natl.Acad.Sci.USA 113 13015 2016
sourceHomo sapiens
experimentX-ray (resolution=3.10, R-factor=?)
structural superfamilyp53-like transcription factors;SH2 domain;STAT;
reference complex4y5w_B
links to other resourcesNAKB PDBSum PDIdb DNAproDB
protein sequence
interface signatureVHNQ/VH

Estimated binding specificities ?

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# IC=4.475 IC/col=0.639 n_of_columns=7 specificity:   
A |   0   0   0  24  24  13  13
C |   0   0  96  24  24  13  13
G |   0   0   0  24  24  54  57
T |  96  96   0  24  24  16  13
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updated Mon Jan 5 12:15:38 2026