interface graph thumbnail
legend  pdf

structure nameCRYSTAL STRUCTURE OF THE DM DOMAIN OF HUMAN DMRT1 BOUND TO 25MER TARGET DNA
(Doublesex- and mab-3-related transcription factor 1)
referenceGearhart et al. Nat.Struct.Mol.Biol. 22 442 2015
sourceHomo sapiens
experimentX-ray (resolution=3.81, R-factor=0.232)
structural superfamilyCysteine-rich DNA binding domain, DM domain;
sequence familyDM DNA binding domain;
multimeric complexes4yj0_ABC
links to other resourcesNAKB PDBSum PDIdb DNAproDB
protein sequence
interface signatureRRMQVRR

Estimated binding specificities ?

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# IC=3.984 IC/col=0.797 n_of_columns=5 specificity:   
A |  11   0  11   0   9
C |   9   0   0   9   9
G |   9  96   9   0  69
T |  67   0  76  87   9
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updated Sat Jan 10 07:40:05 2026