4z1z_A : 3D-footprint complex

structure name	CRYSTAL STRUCTURE OF MEGANUCLEASE I-SMAMI BOUND TO UNCLEAVEABLE DNA WITH A TTCT CENTRAL FOUR (Meganuclease I-SmaMI)
reference	Hallinan et al. Structure 24 862 2016
source	Sordaria macrospora (strain ATCC MYA-333 / DSM 997 / K(L3346) / K-hell) / Sordaria macrospora (strain ATCC MYA-333 / DSM 997 / K(L3346) / K-hell)
experiment	X-ray (resolution=3.20, R-factor=0.240)
structural superfamily	Homing endonucleases;
sequence family	LAGLIDADG endonuclease;
reference complex	5e67_A
links to other resources	NAKB PDIdb DNAproDB
protein sequence	> 4z1z_A interface=19,21,23,28,33,66,74,176,178,180,184,185,190,196,198,220,223,224,227,229,233, sklnpwavvgfidaegsfMvRvRknskYktgwLvvaifsvtvdkkdlflleslktffgglgsikkSgnstfsyRiesseqltkiilpffdkysliteklgdyllfkkvlelmgtkehltqrglekivslkasinkglseelqaafpqcvptprpeinnipdpfwlagfvsgdgsfKsIlKkseSIkvgfQsilvfQiTqhardvklmeslisylgcgfiEkdSRgpWlYytvTnfsdiqgkiipffhqykiigskygdyqdwckialimqnknhltpeglneiralkggmnkgr
interface signature	MRRYLSRKIKSIQQTESRWYT

Estimated binding specificities ?

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# IC=18.972 IC/col=0.825 n_of_columns=23

specificity:

A |   0  96  24  11   0   0   0   0  24  24  24  24  18   0  96   0  24   0   0   0  96   5  11
C |   0   0  24  62  96   0  96  96  24  24  24  24  11  96   0   0  24   0   0   0   0  79  62
G |   0   0  24  11   0   0   0   0  24  24  24  24  11   0   0  96  24   0  96   0   0   7  11
T |  96   0  24  12   0  96   0   0  24  24  24  24  56   0   0   0  24  96   0  96   0   5  12

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updated Fri Jan 9 02:07:05 2026