4z1z_A : 3D-footprint complex

structure name	CRYSTAL STRUCTURE OF MEGANUCLEASE I-SMAMI BOUND TO UNCLEAVEABLE DNA WITH A TTCT CENTRAL FOUR (Meganuclease I-SmaMI)
reference	Hallinan et al. Structure 24 862 2016
source	Sordaria macrospora (strain ATCC MYA-333 / DSM 997 / K(L3346) / K-hell) / Sordaria macrospora (strain ATCC MYA-333 / DSM 997 / K(L3346) / K-hell)
experiment	X-ray (resolution=3.20, R-factor=0.240)
structural superfamily	Homing endonucleases;
sequence family	LAGLIDADG endonuclease;
reference complex	5e67_A
links to other resources	NAKB PDIdb DNAproDB
protein sequence	> 4z1z_A interface=19,21,23,28,33,66,74,176,178,180,184,185,190,196,198,220,223,224,227,229,233, sklnpwavvgfidaegsfMvRvRknskYktgwLvvaifsvtvdkkdlflleslktffgglgsikkSgnstfsyRiesseqltkiilpffdkysliteklgdyllfkkvlelmgtkehltqrglekivslkasinkglseelqaafpqcvptprpeinnipdpfwlagfvsgdgsfKsIlKkseSIkvgfQsilvfQiTqhardvklmeslisylgcgfiEkdSRgpWlYytvTnfsdiqgkiipffhqykiigskygdyqdwckialimqnknhltpeglneiralkggmnkgr
interface signature	MRRYLSRKIKSIQQTESRWYT

Estimated binding specificities ?

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# IC=18.881 IC/col=0.821 n_of_columns=23

specificity:

A |  10   5   0  96   0  96  24   0   0   0  58  24  24  24  24   0   0  96   0  10  24   0  96
C |  10   5   0   0  96   0  24  96   0   0  16  24  24  24  24   0   0   0   0  10  24   5   0
G |  64  81   0   0   0   0  24   0   0  96  12  24  24  24  24  96  96   0  96  64  24   1   0
T |  12   5  96   0   0   0  24   0  96   0  10  24  24  24  24   0   0   0   0  12  24  90   0

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updated Sat Aug 2 07:40:16 2025