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structure nameCRYSTAL STRUCTURE OF MEGANUCLEASE I-SMAMI BOUND TO UNCLEAVEABLE DNA WITH A TTCT CENTRAL FOUR
(Meganuclease I-SmaMI)
referenceHallinan et al. Structure 24 862 2016
sourceSordaria macrospora (strain ATCC MYA-333 / DSM 997 / K(L3346) / K-hell) / Sordaria macrospora (strain ATCC MYA-333 / DSM 997 / K(L3346) / K-hell)
experimentX-ray (resolution=3.20, R-factor=0.240)
structural superfamilyHoming endonucleases;
sequence familyLAGLIDADG endonuclease;
links to other resourcesNAKB PDBSum PDIdb DNAproDB
protein sequence
interface signatureMRRYLSRKIKSIQQTESRWYT

Estimated binding specificities ?

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# IC=18.904 IC/col=0.822 n_of_columns=23 specificity:   
A |  12   5   0  96   0  96  24   0   0   0  58  24  24  24  24   0   0  96   0  10  24   0  96
C |  10   5   0   0  96   0  24  96   0   0  10  24  24  24  24   0   0   0   0  10  24   5   0
G |  64  80   0   0   0   0  24   0   0  96  12  24  24  24  24  96  96   0  96  64  24   0   0
T |  10   6  96   0   0   0  24   0  96   0  16  24  24  24  24   0   0   0   0  12  24  91   0
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updated Tue Dec 17 00:40:01 2024