4z20_D : 3D-footprint complex

structure name	CRYSTAL STRUCTURE OF MEGANUCLEASE I-SMAMI BOUND TO UNCLEAVEABLE DNA WITH A TTGT CENTRAL FOUR (MEGANUCLEASE I-SMAMI)
reference	Hallinan et al. Structure 24 862 2016
source	Sordaria macrospora (strain ATCC MYA-333 / DSM 997 / K(L3346) / K-hell) / Sordaria macrospora (strain ATCC MYA-333 / DSM 997 / K(L3346) / K-hell)
experiment	X-ray (resolution=3.20, R-factor=0.236)
structural superfamily	Homing endonucleases;
sequence family	LAGLIDADG endonuclease;
links to other resources	NAKB PDIdb DNAproDB
protein sequence	> 4z20_D interface=17,19,21,26,31,39,62,64,72,171,173,175,177,181,182,187,193,195,217,219,221,224,226,230, lnpwavvgfidaegsfMvRvRknskYktgwLvvaifsvTvdkkdlflleslktffgglgsiKkSgnstfsyRiesseqltkiilpffdkysliteklgdyllfkkvlelmgtkehltqrglekivslkasinkglseelqaafpqcvptprpeknipdpfwlagfvsgdgSfKsIlKkseSIkvgfQsilvfQiTqhardvklmeslisylgcgfiEkDsRgpWlYytvTnfsdiqgkiipffhqykiigskygdyqdwckialimqnknhltpeglneiralkggmnkgr
interface signature	MRRYLTKSRSKIKSIQQTEDRWYT

Estimated binding specificities ?

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# IC=20.244 IC/col=0.920 n_of_columns=22

specificity:

A |   0  96  24   0   0   0   0  11  24  24  24   7  11   0  96   0   0   0   0   0  96   1
C |   5   0  24  96  96   0  96  73  24  24  24  11  13  96   0   0   5   0   0   0   0  84
G |   7   0  24   0   0   0   0   7  24  24  24  67   5   0   0  96  86   0  96   0   0   0
T |  84   0  24   0   0  96   0   5  24  24  24  11  67   0   0   0   5  96   0  96   0  11

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updated Tue Dec 17 00:40:15 2024