5a78_AB : 3D-footprint complex

structure name	CRYSTAL STRUCTURE OF THE HOMING ENDONUCLEASE I-CVUI IN COMPLEX WITH I- CREI TARGET (C1221) IN THE PRESENCE OF 2 MM MG REVEALING DNA NOT CLEAVED
reference	LopezMendez et al. J.Biol.Chem. 290 28727 2015
source	CHLORELLA VULGARIS
experiment	X-ray (resolution=2.50, R-factor=?)
structural superfamily	Homing endonucleases;
reference complex	5a78_B
links to other resources	NAKB PDIdb DNAproDB
protein sequence	> 5a78_A interface=24,26,28,30,31,36,38,44,66,68,69,70,72,74,138, nfhdqlkfawlagfvdadgcinaQiVsReDYllkyQvRvsltvFqsttqhfilldiqkilgcgtvRkRNDgMsEfcvvggtslqttlekllpylqlkraqaklvlqiikklpntkdpsvlmeaalladkvglltdgkKrtilaenvreclkklghvv > 5a78_B interface=20,24,26,28,30,31,36,38,44,66,68,69,70,72,74,138, nfhdqlkfawlagfvdadgCinaQiVsReDYllkyQvRvsltvFqsttqhfilldiqkilgcgtvRkRNDgMsEfcvvggtslqttlekllpylqlkraqaklvlqiikklpntkdpsvlmeaalladkvglltdgkKrtilaenvreclkklghvvs
interface signature	QVRDYQRFRRNDMEK/CQVRDYQRFRRNDMEK

Estimated binding specificities ?

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# IC=25.359 IC/col=1.153 n_of_columns=22

specificity:

A |   0  92  96  92  96   0   0   5   3   6   3  84   6   0  96   0   0   3  84   0   3   0
C |  96   1   0   0   0  96   0   0  93   3   9   3  84   0   0  96   0   3   6   0   3   0
G |   0   3   0   0   0   0  96   3   0  84   3   6   3  96   0   0  96   3   3   0   2  96
T |   0   0   0   4   0   0   0  88   0   3  81   3   3   0   0   0   0  87   3  96  88   0

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updated Mon Jan 5 13:21:31 2026