5a78_B : 3D-footprint complex

structure name	CRYSTAL STRUCTURE OF THE HOMING ENDONUCLEASE I-CVUI IN COMPLEX WITH I- CREI TARGET (C1221) IN THE PRESENCE OF 2 MM MG REVEALING DNA NOT CLEAVED (DNA ENDONUCLEASE I-CVUI)
reference	LopezMendez et al. J.Biol.Chem. 290 28727 2015
source	CHLORELLA VULGARIS
experiment	X-ray (resolution=2.50, R-factor=0.222)
structural superfamily	Homing endonucleases;
sequence family	LAGLIDADG endonuclease;
multimeric complexes	5a72_AB 5a78_AB
redundant complexes	5a72_B
links to other resources	NAKB PDIdb DNAproDB
protein sequence	> 5a78_B interface=20,24,26,28,30,31,36,38,44,66,68,69,70,72,74,138, nfhdqlkfawlagfvdadgCinaQiVsReDYllkyQvRvsltvFqsttqhfilldiqkilgcgtvRkRNDgMsEfcvvggtslqttlekllpylqlkraqaklvlqiikklpntkdpsvlmeaalladkvglltdgkKrtilaenvreclkklghvvs
interface signature	CQVRDYQRFRRNDMEK

Estimated binding specificities ?

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# IC=12.649 IC/col=1.054 n_of_columns=12

specificity:

A |   7  79   5   0  96   0   0  11  79   0   5   0
C |  11   5  81   0   0  96   0   0   5   0   5   0
G |   5   7   5  96   0   0  96   1   7   0   0  96
T |  73   5   5   0   0   0   0  84   5  96  86   0

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Dendrogram of similar interfaces ?

matrix format

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updated Mon Jun 29 19:08:39 2026