5b2r_B : 3D-footprint complex

structure name	CRYSTAL STRUCTURE OF THE STREPTOCOCCUS PYOGENES CAS9 VQR VARIANT IN COMPLEX WITH SGRNA AND TARGET DNA (TGA PAM) (CRISPR-associated endonuclease Cas9)
reference	Nishimasu et al. Mol.Cell 61 886 2016
source	Streptococcus pyogenes serotype M1
experiment	X-ray (resolution=2.00, R-factor=0.202)
multimeric complexes	7v59_BE
redundant complexes	7s36 7ox7 7s38 7s3h 7ox8 7ox9 7oxa 6o0z 7s4u 7s4v 5b2s 5b2t 6vpc 4oo8 6aeb 6aeg 6ai6 5fw1 5fw2 5fw3 6k3z 6k4p 5y36 6k4q 6k4s 6k4u 6k57 5f9r
reference complex	6vpc_F
links to other resources	NAKB PDIdb DNAproDB
protein sequence	> 5b2r_B interface=1065,1177,1286,1288,1290, kysiglaigtnsvgwavitdeykvpskkfkvlgntdrhsikknligallfdsgetaeatrlkrtarrrytrrknrilylqeifsnemakvddsffhrleesflveedkkherhpifgnivdevayhekyptiyhlrkklvdstdkadlrliylalahmikfrghfliegdlnpdnlfiqlvqtynqlfeenpinasgvdakailsarlsksrrlenliaqlpgekknglfgnlialslgltpnfksnfdlaedaklqlskdtydddldnllaqigdqyadlflaaknlsdaillsdilrvnteitkaplsasmikrydehhqdltllkalvrqqlpekykeiffdqskngyagyidggasqeefykfikpilekmdgteellvklnredllrkqrtfdngsiphqihlgelhailrrqedfypflkdnrekiekiltfripyyvgplargnsrfawmtrkseetitpwnfeevvdkgasaqsfiermtnfdknlpnekvlpkhsllyeyftvyneltkvkyvtegmrkpaflsgeqkkaivdllfktnrkvtvkqlkedyfkkieefdsveisgvedrfnaslgtyhdllkiikdkdfldneenediledivltltlfedremieerlktyahlfddkvmkqlkrrrytgwgrlsrklingirdkqsgktildflksdgfanrnfmqlihddsltfkediqkaqdslhehianlagspaikkgilqtvkvvdelvkvmgrhkpeniviemarnsrermkrieegikelgsqilkehpventqlqneklylyylqngrdmyvdqeldinrlsdydvdaivpqsflkddsidnkvltrsdknrgksdnvpseevvkkmknywrqllnaklitqrkfdnltkaergglseldkagfikrqlvetrqitkhvaqildsrmntkydendklirevkvitlksklvsdfrkdfqfykvreinnyhhahdaylnavvgtalikkypklesefvygkatakyffysnimnffkteitlangeirkrplietngetgeivwdkgrdfatvrkvlsmpqvnivkktevqtggfsKesilpkrnsdkliarkkdwdpkkyggfvsptvaysvlvvakvekgkskklksvkellgitimerssfeknpidfleakgykevkkdliiklpkyslfelengrkrmlasagElqkgnelalpskyvnflylashyepedneqkqlfveqhkhyldeiieqisefskrviladanldkvlsaynkhrdkpireqaeniihlftltnlgapaafkyfdttidRkQyRstkevldatlihqsitglyetridlsqlg
interface signature	KERQR

Estimated binding specificities ?

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# IC=3.714 IC/col=0.929 n_of_columns=4

specificity:

A |  12   0  95   4
C |  12   0   0   5
G |  12  96   0  82
T |  60   0   1   5

scan!

Dendrogram of similar interfaces ?

matrix format

  
  YA----MTTGNG--------   L       +---------6je3_A    
                             +---2 
  ------LG--NT--------   L   !   +---------5x2h_A    
                           --3 
  --RC--------SCATQA--   L   !      +------6wbr_A    
                             +------1 
  ----PGRC----------LT   L          +------6joo_A

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updated Thu Sep 12 20:45:25 2024