interface graph thumbnail
legend  pdf

structure nameCRYSTAL STRUCTURE OF THE STREPTOCOCCUS PYOGENES CAS9 VRER VARIANT IN COMPLEX WITH SGRNA AND TARGET DNA (TGCG PAM)
(CRISPR-associated endonuclease Cas9)
referenceNishimasu et al. Mol.Cell 61 886 2016
sourceStreptococcus pyogenes serotype M1
experimentX-ray (resolution=2.20, R-factor=0.205)
multimeric complexes7v59_BE
reference complex6vpc_F
links to other resourcesNAKB PDBSum PDIdb DNAproDB
protein sequence
interface signatureKERER

Estimated binding specificities ?

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# IC=3.287 IC/col=0.822 n_of_columns=4 specificity:   
A |  12   0   2   5
C |  12   0  88   6
G |  12  95   4  79
T |  60   1   2   6
scan!

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updated Sat Aug 2 08:04:53 2025