5b2t_B : 3D-footprint complex

structure name	CRYSTAL STRUCTURE OF THE STREPTOCOCCUS PYOGENES CAS9 VRER VARIANT IN COMPLEX WITH SGRNA AND TARGET DNA (TGCG PAM) (CRISPR-associated endonuclease Cas9)
reference	Nishimasu et al. Mol.Cell 61 886 2016
source	Streptococcus pyogenes serotype M1
experiment	X-ray (resolution=2.20, R-factor=0.205)
multimeric complexes	7v59_BE
reference complex	6vpc_F
links to other resources	NAKB PDIdb DNAproDB
protein sequence	> 5b2t_B interface=1071,1183,1293,1295,1297, kkysiglaigtnsvgwavitdeykvpskkfkvlgntdrhsikknligallfdsgetaeatrlkrtarrrytrrknrilylqeifsnemakvddsffhrleesflveedkkherhpifgnivdevayhekyptiyhlrkklvdstdkadlrliylalahmikfrghfliegdlnpdnsdvdklfiqlvqtynqlfeenpinasgvdakailsarlsksrrlenliaqlpgekknglfgnlialslgltpnfksnfdlaedaklqlskdtydddldnllaqigdqyadlflaaknlsdaillsdilrvnteitkaplsasmikrydehhqdltllkalvrqqlpekykeiffdqskngyagyidggasqeefykfikpilekmdgteellvklnredllrkqrtfdngsiphqihlgelhailrrqedfypflkdnrekiekiltfripyyvgplargnsrfawmtrkseetitpwnfeevvdkgasaqsfiermtnfdknlpnekvlpkhsllyeyftvyneltkvkyvtegmrkpaflsgeqkkaivdllfktnrkvtvkqlkedyfkkieefdsveisgvedrfnaslgtyhdllkiikdkdfldneenediledivltltlfedremieerlktyahlfddkvmkqlkrrrytgwgrlsrklingirdkqsgktildflksdgfanrnfmqlihddsltfkediqkaqdslhehianlagspaikkgilqtvkvvdelvkvmgrhkpeniviemarnsrermkrieegikelgsqilkehpntqlqneklylyylqngrdmyvdqeldinrlsdydvdaivpqsflkddsidnkvltrsdknrgksdnvpseevvkkmknywrqllnaklitqrkfdnltkaergglseldkagfikrqlvetrqitkhvaqildsrmntkydendklirevkvitlksklvsdfrkdfqfykvreinnyhhahdaylnavvgtalikkypklesefvygdgkatakyffysnimnffkteitlangeirkrplietngetgeivwdkgrdfatvrkvlsmpqvnivkktevqtggfsKesilpkrnsdkliarkkdwdpkkyggfvsptvaysvlvvakvekgkskklksvkellgitimerssfeknpidfleakgykevkkdliiklpkyslfelengrkrmlasarElqkgnelalpskyvnflylashyekpedneqkqlfveqhkhyldeiieqisefskrviladanldkvlsaynkhrdkpireqaeniihlftltnlgapaafkyfdttidRkEyRstkevldatlihqsitglyetridlsqlg
interface signature	KERER

Estimated binding specificities ?

readout + contact

# IC=3.421 IC/col=0.684 n_of_columns=5

specificity:

A |  12   0   2   5  38
C |  12   0  88   6  19
G |  12  96   2  80  23
T |  60   0   4   5  16

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updated Fri Jan 9 02:35:46 2026